This study examined the rearing and management methods, financial profitability, and consumer perceptions towards safe broiler production in Bangladesh. Employing stratified random sampling, 60 participants (30 farmers and 30 consumers) from two sub-districts in Mymensingh district were interviewed. A mix of descriptive, mathematical, and statistical approaches was used for data analysis and representation. This study identified key components of safe broiler management, including brooding, housing, feed and water management, lighting, litter maintenance, medication and vaccination, and biosecurity and hygiene control. A benefit–cost of 1.40 obtained from profitability analysis indicated the profitability of safe broiler farming. Consumer awareness of safe broiler meat was assessed using the Likert scale, highlighting the significance of nutrition, packaging, freshness, taste, and natural ingredients in purchasing decisions. The Logit model revealed that factors such as meat size, freshness, taste, and family income significantly impacted consumer purchasing choices. The main challenges faced by safe broiler producers included high prices and limited availability of feed, day-old chicks, medicine and vaccines, and lack of knowledge. To ensure efficient safe broiler production in Bangladesh, this study recommends the implementation of stable input supplies, accessible credit, skill development, and infrastructure enhancement.