Energy conservation, emission reduction, and green and low carbon are of great significance to sustainable development, and are also the theme of the transformation and upgrading of the manufacturing industry. This paper concentrates on studying the energy-efficient hybrid flowshop scheduling problem with consistent sublots (HFSP_ECS) with the objective of minimizing the energy consumption. To solve the problem, the HFSP_ECS is decomposed by the idea of “divide-and-conquer”, resulting in three coupled subproblems, i.e., lot sequence, machine assignment, and lot split, which can be solved by using a cooperative methodology. Thus, an improved cooperative coevolutionary algorithm (vCCEA) is proposed by integrating the variable neighborhood descent (VND) strategy. In the vCCEA, considering the problem-specific characteristics, a two-layer encoding strategy is designed to represent the essential information, and a novel collaborative model is proposed to realize the interaction between subproblems. In addition, special neighborhood structures are designed for different subproblems, and two kinds of enhanced neighborhood structures are proposed to search for potential promising solutions. A collaborative population restart mechanism is established to ensure the population diversity. The computational results show that vCCEA can coordinate and solve each subproblem of HFSP_ECS effectively, and outperform the mathematical programming and the other state-of-the-art algorithms.