Schistosomiasis in Ipogun: Update Assessment on Endemicity and Efficacy of Praziquantel in Chemotherapy

Oniya, Mobolanle Oladipo

doi:10.9734/ijtdh/2013/2606

Cited by 11 publications

(18 citation statements)

References 16 publications

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“…More so, females had a higher rate of prevalence than the males, which is contrary to previous studies in the same community where males were observed to have higher rate of prevalence than the females (Oniya et al, 2013) and in Edo state by Ugbomoiko (2000). This thus shows that it is the frequency of contact with an infected body of water and not their gender that determines the rate of transmission.…”

Section: Discussioncontrasting

confidence: 98%

“…The overall prevalence rate of S. haematobium was far higher than the prevalence rate recorded in the same Ipogun community the previous year by Oniya et al (2013), considering the fact that this area receives praziquantel on a annual basis, prevalence would be expected to be lower than what was obtained. This persistent high prevalence could be the result of constant contact with the river which acts as source of infection since most of the bore holes dug by the State government are no longer functional, or perhaps due to reduced sensitivity of the parasite to drug regimen.…”

Section: Discussioncontrasting

confidence: 56%

“…The dry season lasts from November to March, and is associated with an increased temperature (Oniya and Olofintoye, 2009). The primary source of water for agricultural and most domestic activities is the "Aponmu" river, flowing through the village; it is this river that serves as the contact site (Oniya et al, 2013). Though there are several bore-hole dug by the state government, most of them however were non-functional, making the people to rely heavily on the river.…”

Section: Study Areamentioning

confidence: 99%

“…Oniya and Olofintoye (2009) also reported a prevalence rate of about 18.22% among school pupils in the Local Government area in 2008. Recently, Oniya et al (2013) recorded a prevalence rate of 18% in five of the primary schools in the village area.…”

Section: Introductionmentioning

confidence: 99%

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Post-treatment assessment of praziquantel efficacy among school-age children infected with schistosomiasis in Ipogun area of Ondo State, Nigeria

Oboh¹,

Idowu²,

Mafe³

et al. 2019

Int. J. Bio. Chem. Sci

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Schistosomiasis, a major public health challenge is caused by trematodes of the genus Schistosoma whose intermediate host is snails. Sub-Saharan African (SSA) carried 85% of the global burden of this infection principally amongst school age children. Similarly, Nigeria bears the highest weight of this highly preventable infection in SSA. Preventive chemotherapy (PC) with 40-60 mg\kg praziquantel (PZQ) annually is the focal control strategy in endemic areas. Despite more than two decades of PZQ usage in Nigeria, the disease is still prevalent in affected communities. Thus, the study sought to assess the current post-treatment efficacy of PZQ use for urinary schistosomiasis among primary school age children of Ipogun village. Urine reagent strip (Haemastix) ® was initially used to screen pupils for haematuria, while Kato-Katz and urine filtration were employed to confirm the presence of schistosome ova in the faeces and urine of the study population pre-and post-treatment. A total of 202 children were screened, out of which 117 (57.9%) were positive for microhaematuria and 91 (45.0%) had ova of Schistosoma haematobium in their urine. The 14 and 21 day post-treatment assessment revealed 73.6% and 23.1% of the initially infected children to still be with infection respectively. Additionally, there was a statistical significant (P=0.02) in the reduction of egg count twenty-one days post-treatment. Though the efficacy of the drug as observed in the egg reduction rate in the study area can be classified as satisfactory, continuous monitoring of schistosome response should not cease if the global target of eliminating morbidity due to schistosomiasis by year 2020 is to be achieved.

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Section: Discussioncontrasting

confidence: 98%

Section: Discussioncontrasting

confidence: 56%

Section: Study Areamentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Post-treatment assessment of praziquantel efficacy among school-age children infected with schistosomiasis in Ipogun area of Ondo State, Nigeria

Oboh¹,

Idowu²,

Mafe³

et al. 2019

Int. J. Bio. Chem. Sci

View full text Add to dashboard Cite

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“…Duncan's New Multiple Range Test at (p≤0.05). [19,20] who in their study on the assessment of edemicity of prazinquatel where Ipogun-Ayo had the highest prevalence of 18.0%. This present study also implicated Ipogun-Ayo to have the highest prevalence of (28.72%).…”

Section: Difference Between Means Was Determined Bymentioning

confidence: 98%

Prevalence and Antibiogram Characteristics of Bacteriuria and Cadidiuria among Indigenes of Selected Parts of Akure North, Ondo State

Bodunrinde

Olusola-Makinde

Oladunmoye

2019

JAMB

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Aims: The aim of this study was to evaluate the prevalence and antibiogram characteristics of bacteria and fungi in urine samples of some selected towns in Ondo State, Nigeria. Study Design: Experimental design. Study Location: Urine samples were collected from patients visiting University of Medical Science Teaching Hospital Akure and indigenes of Ogbese, Ipogun-Ayo and Ita-oniyan community in Ondo North, Nigeria. Methodology: Pre-survey of the study participants was carried out using randomly distributed questionnaires. Two hundred and forty-three (243) urine samples were randomly collected from apparently healthy male and female participants cutting across different age groups. Presumptive identification of isolated bacteria and fungi were cultured on general and differential media (cysteine lactose electrolyte deficient agar, blood agar, nutrient agar, and Potato dextrose agar, for fungal isolates) were done using standard methods. The clinical and relative typed isolates were collected from Federal Institute of Industrial Research Oshodi (FIIRO) and were subjected to antibiotic sensitivity pattern using array of ten (10) conventional antibiotics according to Clinical Laboratory Standard Instruction. Results: Stapylococcus aureus was the most frequently occurred (27.2%) bacteria isolated from the urine samples while, Candida albicans had the least (5.6%) occurrence. These findings revealed that bacteriuria and candidiuria were prevalent among the indigenes of Ipogun-Ayo, Ondo State, with antibiotic sensitivity to few conventional antibiotics. This is an indication of UTI among the indigenes and urgent need for medical attention.

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Environmental factors influencing the distribution and prevalence ofSchistosoma haematobiumin school attenders of ILembe and uThungulu Health Districts, KwaZulu-Natal Province, South Africa

Banhela

Taylor

Zulu

et al. 2017

Southern African Journal of Infectious Diseases

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Schistosomiasis in Ipogun: Update Assessment on Endemicity and Efficacy of Praziquantel in Chemotherapy

Cited by 11 publications

References 16 publications

Post-treatment assessment of praziquantel efficacy among school-age children infected with schistosomiasis in Ipogun area of Ondo State, Nigeria

Post-treatment assessment of praziquantel efficacy among school-age children infected with schistosomiasis in Ipogun area of Ondo State, Nigeria

Prevalence and Antibiogram Characteristics of Bacteriuria and Cadidiuria among Indigenes of Selected Parts of Akure North, Ondo State

Environmental factors influencing the distribution and prevalence ofSchistosoma haematobiumin school attenders of ILembe and uThungulu Health Districts, KwaZulu-Natal Province, South Africa

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