Schizandrin A enhances the sensitivity of gastric cancer cells to 5-FU by promoting ferroptosis
Liye Hu,
Zhongyuan Zhang,
Yun Fu
et al.
Abstract:Objectives
The impact of Schizandrin A (Sch A) on 5-fluorouracil (5-Fu) in gastric cancer (GC) cells is not yet understood, despite its known anticancer and multidrug resistance-reversing properties in various tumors. The objective of this study was to investigate the ability of Sch A to reverse resistance and evaluate its mechanisms in GC cells that are resistant to 5-Fu.
Methods
5-Fu-sensitive gastric cancer (GC) cells were… Show more
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