Schizophrenic Psychosis and Associated Aqueduct Stenosis

O'Flaithbheartaigh, Séamus; Williams, Pearse; Jones, Gareth H.

doi:10.1192/bjp.164.5.684

Cited by 14 publications

(7 citation statements)

References 8 publications

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“…Epilepsy has been reported to occur in patients with AS in more than 15% of the cases (40)(41)(42)(43). Schizophrenia, believed to be associated with dysfunction in diencephalon/mesencephalon, has been reported to be over-represented in AS (21,(44)(45)(46).…”

Section: Symptomatologymentioning

confidence: 99%

How should primary aqueductal stenosis in adults be treated? - A review

Tisell

2005

Acta Neurol Scand

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In 10% of adult patients with hydrocephalus, the cause is because of aqueductal stenosis (AS), causing enlargement of the lateral and third ventricles. There are currently two alternate forms of surgical treatment for AS; shunt surgery and ventriculostomy. Shunt surgery is associated with high complication rates and many patients need revisions, but the effectiveness is high. Endoscopic third ventriculostomy (ETV), re-establishing a physiological route of CSF dynamics, has become the treatment of choice for AS in most neurosurgical centers. ETV has fewer complications and revisions are rare, but some patients need shunt surgery to improve despite a patent ventriculostomy. There are today no common criteria for patient selection to either ETV or ventriculo-peritoneal shunt surgery.

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Section: Symptomatologymentioning

confidence: 99%

How should primary aqueductal stenosis in adults be treated? - A review

Tisell

2005

Acta Neurol Scand

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“…Normal‐pressure hydrocephalus is a common cause of a potentially reversible dementia that can present with psychiatric manifestations such as psychosis 10 . Further reports in the literature support the connection between psychosis and hydrocephalus, 11 but the role of vasospasm as a contributing factor for psychosis has been discussed in a case of post‐traumatic SAH 12 . This patient’s thought disorder improved as the vasospasm was successfully treated.…”

Section: Discussionmentioning

confidence: 99%

Psychiatric presentation of aneurysmal subarachnoid haemorrhage

Mobbs

Chandran

Newcombe

2001

ANZ Journal of Surgery

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“…These childhood forms of stenosis are more dangerous and have been studied more extensively than adult forms, although the latter have not been uncommon [9]. Aqueductal stenosis and the slightest alterations in the position, shape, and size of the aqueduct have serious effects on the function of the midbrain structures, and can lead to different neurologic disturbances (hydrocephalus, spastic paresis, muscular rigidity), and may be accompanied by divergence paralysis [10], hydrocephalus [8,9], schizophrenia and parkinsonism [11,12,13], as well as periaqueductal dysfunction (the sylvian aqueduct syndrome) [14].…”

Section: Introductionmentioning

confidence: 99%

Anatomical and MRI relations of the cerebral aqueduct to the adjacent parts of the brain and calvaria

Stanković¹,

Vitošević²,

Bexheti

et al. 2017

Srp Arh Celok Lek

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Introducton/Objective Insufficiency of relevant anatomic data and great neurological and neurosurgical significance were the reasons for this study with scientific and practical implications. The purpose was to determine, at the transverse in situ section of the head, the position and relations of the sylvian aqueduct of the mesencephalon by measuring its distances from particular brain and calvaria structures. Also, the aim was to determine the same distances according to axial sections by using MRI. Methods The material consisted of twenty autopsy human heads. The section of the head was made at the level of the tentorial hiatus and the midbrain. After that, we measured the distances between the cerebral aqueduct and a) posterior border of the optic chiasm, b) upper border of the dorsum sellae, c) terminal bifurcation of the basilar artery, d) beginning of the straight sinus, e) internal occipital protuberance, f) tentorial edge (lateral from the aqueduct), and g) internal surface of the calvaria (lateral to the aqueduct). We determined the same distances by the MRI system. The measurements were made in 37 subjects. Results The numerical data obtained by this study will be of benefit to neurosurgeons in choosing a surgical approach to the contents of the incisural space, and to neurologists for the exact localization of the lesion and interpretation of certain signs and symptoms. Conclusion The results of a detailed examination of the sylvian aqueduct position and relations have shown that the use of MRI is the morphometric method of choice, because it is more precise for all the parameters monitored than in situ measurements.

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Schizophrenic Psychosis and Associated Aqueduct Stenosis

Abstract: In two adults, both schizophrenia and hydrocephalus were associated with aqueduct stenosis. The prevalence is argued to be above chance, and may contribute to the neurodevelopmental hypothesis of the causality of schizophrenia.

Cited by 14 publications

References 8 publications

How should primary aqueductal stenosis in adults be treated? - A review

How should primary aqueductal stenosis in adults be treated? - A review

Psychiatric presentation of aneurysmal subarachnoid haemorrhage

Anatomical and MRI relations of the cerebral aqueduct to the adjacent parts of the brain and calvaria

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