Schwannoma of Upper Lip: Report of a Rare Case in a Rare Age Group

Hajong, Ranendra; Hajong, Debobratta; Naku, Narang; Sharma, Girish Kumar; Boruah, Manash Pratim

doi:10.7860/jcdr/2016/20888.8395

Cited by 7 publications

(11 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Only three cases of recurrent malignant lip schwannoma have been documented, but recurrence is unlikely with complete resection. [21114] If recurrence occurs, it needs to consider whether complete enucleation is achieved or malignant transformation is a possibility. [11] In general, the prognosis of schwannoma is quite favorable.…”

Section: Discussionmentioning

confidence: 99%

Lower lip plexiform schwannoma: Report of a rare case and a literature review

Yaghoobi

Pazyar

2019

Indian J Dermatol

View full text Add to dashboard Cite

Plexiform schwannoma is an uncommon benign neoplasm of the neural sheath characterized grossly and microscopically by multinodular growth. It is typically presented as a mobile, solitary, smooth-surfaced, and nontender mass. Histologically, schwannomas are classified into the following seven types: classical (Verocay), plexiform, cellular, cranial nerve, melanotic, degenerated (ancient), and granular cell schwannomas. In spite of the fact that plexiform schwannoma commonly occurs in the head-and-neck region, the involvement of the lip is considered to be extremely rare. Herein, we present the case of a 16-year-old boy with the schwannoma on the lower lip excised without any recurrence at 9 months after surgery.

show abstract

Section: Discussionmentioning

confidence: 99%

Lower lip plexiform schwannoma: Report of a rare case and a literature review

Yaghoobi

Pazyar

2019

Indian J Dermatol

View full text Add to dashboard Cite

show abstract

“…[3][4][5]7,9,15,16 Furthermore, Schwannomas of the lip is the rarest reported clinical entity and is therefore generally not included in the differential diagnosis of a lower lip swelling. 1,3,6,10,12,14,17,20 Schwannoma of the lip was first described in 1969 and since then only a few number of Schwannoma cases of the lip have been reported. 12,18 Moreover, as the Schwannoma of the lip enlarges, it also causes obvious aesthetic disfigurement for the patient and can lead to emotional distress.…”

Section: Acronymsmentioning

confidence: 99%

Oral Medicine Case Book: An intra-oral solitary Schwannoma of the lower lip, a rare diagnosis

et al. 2019

View full text Add to dashboard Cite

“…Although the lips and oral cavity are highly innervated anatomic regions, only 1% of schwannomas originate from peripheral nerves in the intraoral cavity . Schwannoma of the upper and lower lips presents as a painless mass with conventional histology demonstrating Antoni A (Verocay) patterns of nuclear palisades surrounding cellular bodies alternating with hypocellular Antoni B patterns . Positive staining for the S‐100 protein in immunohistochemical staining is a classic marker for diagnostic confirmation, and magnetic resonance imaging (MRI) is the gold standard for preoperative imaging; however, imaging modalities are not considered routine or necessary .…”

Section: Introductionmentioning

confidence: 99%

“…Positive staining for the S‐100 protein in immunohistochemical staining is a classic marker for diagnostic confirmation, and magnetic resonance imaging (MRI) is the gold standard for preoperative imaging; however, imaging modalities are not considered routine or necessary . Schwannomas are typically solitary, smooth, slow‐growing, freely mobile, and minimally invasive tumors; thus, complete surgical excision is the standard of care for ensuring limited physical disfigurement and recurrence …”

Section: Introductionmentioning

confidence: 99%

“…Complete surgical excision typically leads to favorable outcomes without recurrence . The lips are a rare location for this tumor; thus, a diagnosis of lip schwannoma is often overlooked until more progressive stages of growth and cosmetic disfigurement . Although schwannomas represent benign peripheral tumors, the histology of larger lip schwannomas can often be misleading, causing a false diagnosis of malignancy and unnecessary emotional distress for the patient .…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Clinical features and management of schwannoma affecting the upper and lower lips

et al. 2018

View full text Add to dashboard Cite

Head and neck schwannomas comprise 25-40% of all schwannomas, with presentation on the lips as the rarest and most surgically complicated site for perioral tumors. A systematic literature review was conducted to include 21 cases of patients with schwannoma of the upper or lower lips. The majority of patients presented with a single, painless, well-encapsulated nodule on the upper or lower lips. The nodules were consistently slow-growing, with an average 29.3 months from symptom onset to clinical presentation. Most cases were complicated by profound cosmetic disfigurement as well as dysphagia, dysarthria, snoring, and/or sleep apnea. Overall, histological analysis was consistent with classic schwannoma, and all cases were treated via complete surgical excision, and for malignant tumors, additional therapy was utilized. All but four cases achieved full remission by final follow-up. Recurrence rate for benign lip schwannomas was 5.3%, which is remarkably different from the standard recurrence rate of 8-24% for benign peripheral schwannomas. Additionally, the proportion of malignant tumors was greater for lip schwannomas than other schwannomas. Lip schwannomas demonstrate different characteristics than schwannomas from other locations on the body, and these remarkable differences highlight significant implications for clinical practice. Complete excision is the primary mode of treatment with overall excellent postoperative prognosis and rare instances of recurrence. Given the rarity of this tumor, this review of available cases serves to comprehensively describe clinical presentation and surgical treatment approaches to upper and lower lip schwannomas.

show abstract

Schwannoma of Upper Lip: Report of a Rare Case in a Rare Age Group

Cited by 7 publications

References 5 publications

Lower lip plexiform schwannoma: Report of a rare case and a literature review

Lower lip plexiform schwannoma: Report of a rare case and a literature review

Oral Medicine Case Book: An intra-oral solitary Schwannoma of the lower lip, a rare diagnosis

Clinical features and management of schwannoma affecting the upper and lower lips

Contact Info

Product

Resources

About