Schwartz–Jampel syndrome: Is risk of malignant hyperthermia the same as that of the general population?

Schwartz-Jampel syndrome is a high risk of difficult airway management rather than malignant hyperthermia

“…[ 1 ] However, I want to highlight the following considerations: First , the risk of malignant hyperthermia (MH) in association with Schwartz-Jamel syndrome (SJS) is not supported by scientific evidence. [ 2 ] It is concluded that SJS patients have a risk of developing MH that is equivalent to that of the general population,[ 3 ] and Godai stated that SJS is not related to MH. [ 4 ] Second , spinal anesthesia may be an effective, safe and preferred anesthetic technique in patients with SJS and should be preceded by a neurological examination, radiological, and haematological investigation with special attention to the coagulation profile.…”

Comment on “Schwartz–Jampel syndrome: Is risk of malignant hyperthermia the same as that of the general population?”

“…and “Schwartz–Jampel syndrome: Is risk of malignant hyperthermia the same as that of the general population?” by Ayeko. [ 1 2 ] The authors of the case report stated that patients with Schwartz–Jampel syndrome have “an increased risk of malignant hyperthermia.” Ayeko pointed out that “patients with Schwartz–Jampel syndrome are at an increased risk of malignant hyperthermia is not supported by evidence”. I agree with Ayeko, and I have already reported that “Schwartz–Jampel syndrome is not related to malignant hyperthermia” in 2017.…”