1997
DOI: 10.1148/radiology.205.2.9356645
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Sciatic nerve: paradoxic hypertrophy after amputation in young patients.

Abstract: Hypertrophy of the sciatic nerve occurred after above-knee amputation in young patients. This finding differed from atrophy of the nerve that has been reported previously in older patients.

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Cited by 10 publications
(19 citation statements)
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“…HILL et al did not mention enhancement of the hypertrophied sciatic nerves, but a heterogeneous enhancement pattern was reported for amputation neuromas (4,8). Focal enhancement of the nerve could be misinterpreted as a recurrent metastatic lesion, but examining the nerve tissue along its full length is important for excluding recurrent lesions.…”
Section: Discussionmentioning
confidence: 99%
“…HILL et al did not mention enhancement of the hypertrophied sciatic nerves, but a heterogeneous enhancement pattern was reported for amputation neuromas (4,8). Focal enhancement of the nerve could be misinterpreted as a recurrent metastatic lesion, but examining the nerve tissue along its full length is important for excluding recurrent lesions.…”
Section: Discussionmentioning
confidence: 99%
“…Rarely, paradoxical sciatic nerve stump hypertrophy can develop in young patients who underwent limb amputation, in contrast to neural atrophy, which is characteristic in older patients [33,34] (Figure 9). Residual limb pain post amputation is often referred to as ''stump pain'' and has been described in up to 60% of patients [35].…”
Section: Miscellaneousmentioning
confidence: 99%
“…Paradoxic sciatic nerve hypertrophy has been reported following lower limb amputation for malignant [1] and nonmalignant [2] conditions. Nerve hypertrophy is greatest near the transection site and extends proximally.…”
mentioning
confidence: 99%
“…Nerve hypertrophy is greatest near the transection site and extends proximally. It is termed paradoxical because proximal nerve atrophy usually ensues after transection [1]. Larger nerve diameters are associated with higher amputation level and longer duration after surgery, but not with pain complaints.…”
mentioning
confidence: 99%
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