Introduction: Identifying determinants of prevention behaviours during the emergence of an infectious disease and pandemic is important. We aimed to investigate associations between information-seeking and prevention behaviours, as well as the mediating effects of psychiatric factors, during the coronavirus disease (COVID-19) pandemic.
Methods: A total of 1970 participants from the Cardiovascular and Metabolic Etiology Research Center cohort participated in an online survey 55 days after the first diagnosed case of COVID-19 in South Korea. Time spent seeking COVID-19-related information; information sources; psychiatric factors, including anxiety, depression, posttraumatic stress symptoms (PTSS), and fear of COVID-19; and prevention behaviours were queried. The mediating effect of psychiatric factors was estimated using mediation analyses.Results: Time seeking information and information sources affected several behavioural responses. In men, anxiety mediated associations between information-seeking and prevention behaviours, including purchasing sanitary supplies (effect size, 0.038; 95% confidence interval, 0.002-0.095) and hoarding (0.029, 0.002-0.068). Fear of COVID-19 mediated association between information search and preventive behaviours including refraining from going out