Science teaching in junior high schools should be conducted in integrated form. However, the real condition shows that in implementing the integrated science teaching in the schools was found problem. The solution of this problem is to develop integrated science teaching materials by integrating real-world context and scientific literacy on Science teachers in East Agam district. The objective of theactivity is to assist science teachers in developing integrated science teaching material and apply it in science teaching in the classroom. Participants of program assistance were 40 science teachers who were members of the Science MGMP in East Agam district. The instrument for collecting data consisted of pretest and posttest, performance assessment sheet, and questionnaire sheet. The data were analyzed by descriptive statistics analysis and correlated comparison test. Based on the results of data analysis can be stated that: 1). The validity of the integrated science instructional materials in theassistance program can be entered into the good category, 2). The practicality average value of using integrated science instructional material according to students can be grouped into very good category, 3). The average value of the science teacher's response to the implementation of program assistance for the development of integrated science teaching material can be classified into very good category, and 4). The implementation of the program assistance for the development of integrated science teaching material is effective to improve the understanding of science teachers on the material of instructionalmaterial, the concept of integrated science teaching, and the concept of scientific literacy.