Scientific and Theoretical Validation of Development of Personalized Anti-Cancer Cell Preparation Onthe Bases of Clinical Oncoproteomics Technology

Bryukhovetskiy, Igor; Степанович, Брюховецкий Игорь; Bryukhovetskiy, Andrey; Степанович, Брюховецкий Андрей

doi:10.17816/clinpract5144-60

Cited by 1 publication

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“…Relying on genomic, transcriptomic, and proteomic research regarding NT cells in health and disease 8,[47][48] and our work in theoretical neurology, we have developed the following information principles of brain operation.…”

Section: Principles Of Human Brain Operationmentioning

confidence: 99%

Novel theory of the human brain: information-commutation basis of architecture and principles of operation

Bryukhovetskiy¹

2015

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Based on the methodology of the informational approach and research of the genome, proteome, and complete transcriptome profiles of different cells in the nervous tissue of the human brain, the author proposes a new theory of information-commutation organization and architecture of the human brain which is an alternative to the conventional systemic connective morphofunctional paradigm of the brain framework. Informational principles of brain operation are defined: the modular principle, holographic principle, principle of systematicity of vertical commutative connection and complexity of horizontal commutative connection, regulatory principle, relay principle, modulation principle, "illumination" principle, principle of personalized memory and intellect, and principle of low energy consumption. The author demonstrates that the cortex functions only as a switchboard and router of information, while information is processed outside the nervous tissue of the brain in the intermeningeal space. The main structural element of information-commutation in the brain is not the neuron, but information-commutation modules that are subdivided into receiver modules, transmitter modules, and subscriber modules, forming a vertical architecture of nervous tissue in the brain as information lines and information channels, and a horizontal architecture as central, intermediate, and peripheral information-commutation platforms. Information in information-commutation modules is transferred by means of the carriers that are characteristic to the specific information level from inductome to genome, transcriptome, proteome, metabolome, secretome, and magnetome. In the brain, the pia mater is an information carrier and the arachnoid is a system administrator and a software carrier. Horizontal commutation between different parts of the brain proceeds extraneurally in holograms formed by the interference and diffraction of reference and object electromagnetic waves of the information-commutation modules of the brain cortex in cerebrospinal fluid. Vertical commutation of the information-commutation modules of various information-commutation platforms is achieved by package impulse transfer of current along axons, and horizontal commutation is performed biochemically by secretomes of cells and synapses in the nervous tissue of the brain. Practical application of this novel theory is demonstrated in an explanation of the pathogenesis and clinical symptoms of several nervous system and psychiatric diseases.

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Section: Principles Of Human Brain Operationmentioning

confidence: 99%

Novel theory of the human brain: information-commutation basis of architecture and principles of operation

Bryukhovetskiy¹

2015

View full text Add to dashboard Cite

show abstract

Scientific and Theoretical Validation of Development of Personalized Anti-Cancer Cell Preparation Onthe Bases of Clinical Oncoproteomics Technology

Cited by 1 publication

References 6 publications

Novel theory of the human brain: information-commutation basis of architecture and principles of operation

Novel theory of the human brain: information-commutation basis of architecture and principles of operation

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