Background: The wide use of digital tools in teaching requires a hygienic assessment of their impact on the health and lifestyle of students. The objective of the study was to assess the impact of the digital environment on the health and lifestyle of adolescents, depending on the duration of use of electronic learning tools in educational and leisure activities. Methods: An anonymous online questionnaire-based survey of 111 high school and college students was conducted to establish their screen time in the educational process, when performing homework and at leisure, as well as indicators of wellbeing and lifestyle and health complaints. In addition, learning conditions in college computer classes, such as illumination, microclimate, air ionization, levels of electromagnetic fields, airborne concentrations of phenol and formaldehyde were assessed. Modern statistical methods (Student’s t-test, chi-squared test) and methods of evidence-based medicine were applied. Results and discussion: Almost 66 % of the respondents reported using electronic teaching aids (a computer or laptop) at school three or more times a week and severer symptoms of fatigue after such classes. Complaints typical of adult professional users were not common in adolescents, except for visual impairment over the past year (48.6 %). In computer classes, microclimate parameters were far from being optimal: illumination was lower than the regulated values; the levels of electromagnetic fields, ionization, and indoor air concentrations of phenol and formaldehyde were comparable to the appropriate standard values. We observed a high involvement of adolescents in the use of digital tools at home for educational purposes and especially at leisure. The intensive use of Internet (more than 4 hours a day) was associated with frequent complaints of headaches, visual impairment, sleep disorders, and poor self-assessment of the physical shape that may be attributed to the established decreasing number of teenagers engaged in physical culture and sports. Conclusion: The length of time spent in the Internet space for homework and leisure activities affects students’ health and lifestyle. This indicates the need to develop and implement preventive and educational programs for adolescents in order to minimize health risks posed by digital environment and confirmed by outcomes of distance learning.