Scientific Evaluation of Pharmacological Treatment of Osteoarthritis in the Canon of Medicine

Abstract

Osteoarthritis is the most common articular disease worldwide. Nonetheless, common osteoarthritis treatments are either not effective or associated with side effects. Now the materials derived from plants have found a relevant place in drug discovery. Until the mid-18th century, osteoarthritis in all medical schools worldwide had been managed as general arthritis. Avicenna, the famous scholar of Iranian traditional medicine has provided a long list of herbs that have been used traditionally to treat arthritis. To gain this worthy list, we searched his most famous medical masterpiece: Canon of Medicine Some of these materials are investigated and employed by modern medicine. However, it is difficult to ignore that still more of these naturally occurring materials could be of use in modern medicine not only to prevent osteoarthritis progression but also osteoarthritis management as natural anti-inflammatory drugs.

Effect of an orally formulated processed black cumin, from Iranian traditional medicine pharmacopoeia, in relieving symptoms of knee osteoarthritis: A prospective, randomized, double-blind and placebo-controlled clinical trial

“…ITM has a wide range of remedies introduced for the treatment of joint pains such as in the knee . Although N. sativa is not the most frequently recommended plant for treating joint pains, it is a revere plant widely utilized either as a drug for treating conditions or as a spice, especially in baking and pickling, by Iranian people . The fixed oil of this plant has been previously examined in rheumatoid arthritis (RA).…”

Potential metabolites of Arecaceae family for the natural anti-osteoarthritis medicine: A review

“…This disease is caused by the lack of synovial fluid and the components of the cartilage matrix, which impact cartilage damage, pain, deformity, and limited movement [ 1 , 2 , 3 ]. Drugs and nutraceuticals have been widely used to treat this degenerative disorder [ 4 , 5 , 6 ].…”