The delegation of authority in research funding to multi-actor networks that include users is seen as a way to make research more responsive to users' needs. This paper analyzes multi-actor networks for the planning and execution of agricultural research in The Netherlands. It shows that delegation of authority to networks also generates several tensions, and requires substantial role adjustments and institutional learning for the actors involved (government, researchers, intermediaries such as research councils, and user groups) in order to effectively operate in the network. The paper indicates that the principal-agent perspective often used for analyzing the science-policy relationship can be a useful tool for analyzing the multilateral relationships in networks, but needs to be complemented by theories that better capture the notion of co-production in such 'webs of cross-cutting ties'.