Scintigraphic Diagnosis of Bile Leakage after Laparoscopic Cholecystectomy: A Prospective Study

Bile leakage after laparoscopic cholecystectomy demonstrated with99mTc-PMT hepatobiliary scintigraphy

“…They also reported that, in four patients without clinical symptoms, there was a minimal accumulation of activity in the right paracolic gutter. 6 In our patient, following the injection of 99 mTc-PMT, increased activity was seen in the lesser sac, in the right and left paracolic gutter, and in the pouch of Douglas (Figs. 1, 2).…”

“…12 Among them, hepatobiliary scintigraphy has proven a valuable procedure as it provides a sensitive noninvasive assessment of bile leakage, ductal obstruction and complications. [6][7][8][9] Weissmann et al 13 reported that ssmTc -IDA imaging is a simple, noninvasive way to detect the presence of a bile leak following cholecystectomy. Pasmans et als reported the role of ssmTc-HIDA cholescintigraphy in diagnosing bile leakage after laparoscopic cholecystectomy.…”

“…5 Complication following this procedure can occur in the bile duct and most commonly leads to bile duct obstruction or bile leakage. 6 Hepatobiliary scintigraphy is a noninvasive method for examining the bile ducts and looking for bile leakage. [6][7][8][9] 99m Tc-Sn-N-pyridoxyl-5-methyltryptophan (99mTc-PMT) has more rapid blood clearance and hepatobiliary transit than any other hepatobiliary agent.…”

“…6 Hepatobiliary scintigraphy is a noninvasive method for examining the bile ducts and looking for bile leakage. [6][7][8][9] 99m Tc-Sn-N-pyridoxyl-5-methyltryptophan (99mTc-PMT) has more rapid blood clearance and hepatobiliary transit than any other hepatobiliary agent. 10 Less 99 mTc-PMT than 99 mTc-DEIDA is less excreted in the urine, and 99 mTc-PMT is superior in that biliary excretion of the radioactivity is less likely to be suppressed in hyperbilirubinemia.…”

Biliary Peritonitis after Radiofrequency Ablation Diagnosed by Gadoxetic Acid-Enhanced MR Imaging

“…Moreover, the visualization level may vary depending on the location and severity of the bile duct injury. The leakage of bile after cholecystectomy was evaluated by enhanced T1-weighted MR imaging performed about 30 minutes after MnDPDP administration in one report ( 3 ), and cholecystectomy-induced bile leakage was observed at 30 minutes after the administration of a contrast agent with hepatobililary scintigraphy or CT cholangiography after the administration of biliary intravenous contrast medium in other reports ( 9 , 10 ). These studies suggest that the presence and exact location of bile leakage can be evaluated in images obtained within a relatively short time after the administration of a contrast agent, because a large volume of bile is leaked through the large bile duct.…”