Scleractinium Coral Aquaculture Skeleton: a Possible 3D Scaffold for Cell Cultures and Bone Tissue Engineering

Сергеева, Н. С.; Britaev, T. A.; Свиридова, И. К.; Ахмедова, С. А.; Кирсанова, В. А.; Попов, А. А.; Antokhin, A. I.; Франк, Г. А.; Каприн, А. Д.

doi:10.1007/s10517-014-2385-4

Cited by 8 publications

(8 citation statements)

References 7 publications

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“…Sergeeva et al [ 147 ] studied the cytocompatibility and biocompatibility of five coral scaffolds derived from Acroporidae and Pocilloporidae . Cytocompatibility was in vitro evaluated using human fibroblasts and by the formazan assay (MTT), and their biocompatibility was in vivo studied by implantation of the scaffolds into bone defects in rats.…”

Section: Marine-derived Bioceramics As Scaffolds For Bone Tissue Ementioning

confidence: 99%

Synthetic and Marine-Derived Porous Scaffolds for Bone Tissue Engineering

Neto

Ferreira

2018

Materials

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Bone is a vascularized and connective tissue. The cortical bone is the main part responsible for the support and protection of the remaining systems and organs of the body. The trabecular spongy bone serves as the storage of ions and bone marrow. As a dynamic tissue, bone is in a constant remodelling process to adapt to the mechanical demands and to repair small lesions that may occur. Nevertheless, due to the increased incidence of bone disorders, the need for bone grafts has been growing over the past decades and the development of an ideal bone graft with optimal properties remains a clinical challenge. This review addresses the bone properties (morphology, composition, and their repair and regeneration capacity) and puts the focus on the potential strategies for developing bone repair and regeneration materials. It describes the requirements for designing a suitable scaffold material, types of materials (polymers, ceramics, and composites), and techniques to obtain the porous structures (additive manufacturing techniques like robocasting or derived from marine skeletons) for bone tissue engineering applications. Overall, the main objective of this review is to gather the knowledge on the materials and methods used for the production of scaffolds for bone tissue engineering and to highlight the potential of natural porous structures such as marine skeletons as promising alternative bone graft substitute materials without any further mineralogical changes, or after partial or total transformation into calcium phosphate.

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Section: Marine-derived Bioceramics As Scaffolds For Bone Tissue Ementioning

confidence: 99%

Synthetic and Marine-Derived Porous Scaffolds for Bone Tissue Engineering

Neto

Ferreira

2018

Materials

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“…The structure of Goniopora resembles more that of cancellous bone with a porosity >70% and larger pore sizes [129,130]. 6.1.1.1 Natural and partial transformed corals Sergeeva et al [132] studied the cytocompatibility and biocompatibility of 5 coral scaffolds derived from Acroporidae and Pocilloporidae. Cytocompatibility was in vitro evaluated using human fibroblast and by the formazan assay (MTT) and their biocompatibility was in vivo studied by implantation of the scaffolds into bone defects in rats.…”

Section: Coral-derived Bone Grafts Substitutesmentioning

confidence: 99%

“…Cytocompatibility was in vitro evaluated using human fibroblast and by the formazan assay (MTT) and their biocompatibility was in vivo studied by implantation of the scaffolds into bone defects in rats. All of the specimens were cytocompatible and biocompatible [132]. A comparison between coral and autograft was accomplished by Puvanesway et al [133] with the aim to study their morphological and chemical composition as well as the osteogenic differentiation potential in vitro using rabbit mesenchymal stem cells (MSCs).…”

Section: Coral-derived Bone Grafts Substitutesmentioning

confidence: 99%

Synthetic and Marine-Derived Porous Bone Graft Substitutes

Neto¹,

Ferreira²

2018

Preprint

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Bone is a dynamic tissue with the capacity of repair and regeneration in specific conditions. Nevertheless, due to the increased incidence of bone disorders, the need of bone grafts has been growing over the past decades and the development of a bone graft with optimal properties remains a clinical challenge. This review addresses the bone properties (morphology, composition and their repair and regeneration capacity) and then is focused on the potential strategies for bone repair and regeneration. It describes the requirements for designing a suitable scaffold material, types of materials (polymers, ceramics and composites) and techniques to obtain the porous structures (additive manufacturing techniques/robocasting or derived from marine skeletons) for bone tissue engineering applications. The main objective of this review is to gather the knowledge on the materials and methods for the production of scaffolds for bone tissue engineering and highlight that natural materials, namely the marine skeletons represent a promising alternative.

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“…Thus, only capacitor C 2 's charging current contributes Hydrogel's formation. Then hydrogel's expression can be achieved by substituting C 2 's charging current to Equation (15), and hydrogel's height can be expressed as the following equation:…”

Section: Hydrogel's Growth Modelmentioning

confidence: 99%

“…Control of culture matrix can also be used in design and analysis of biosensors for drug test and toxin detection, since cells have their recognition and reaction mechanisms to external stimulus and cells would show different signals when they are cultured in matrix of different patterns [11,12]. In addition, because control of culture matrix includes locating cells precisely, it can be adopted to fabricate tissue mimics, e.g., blood vessels and bones, with certain cell patterns and microarchitecture in tissue engineering [13][14][15]. Therefore, how to construct the hydrogel in 3D space with high controllability has been an urgent demand in biomedical engineering.…”

Section: Introductionmentioning

confidence: 99%

Paper-Based Electrodeposition Chip for 3D Alginate Hydrogel Formation

et al. 2015

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Hydrogel has been regarded as one significant biomaterial in biomedical and tissue engineering due to its high biocompatibility. This paper proposes a novel method to pattern calcium alginate hydrogel in a 3D way via electrodeposition process based on a piece of paper. Firstly, one insulating paper with patterned holes is placed on one indium tin oxide (ITO) glass surface, which is put below another ITO glass. Then, 1% sodium alginate solution with 0.25% CaCO 3 nano particles is filled between these two glasses. In the bottom glass, patterns of electrodes followed patterns of holes on the insulating layer. Hydrogel forms on patterned electrodes when electrochemical potential is applied due to electrodeposition. The experiments demonstrate that the pattern of alginate hydrogels follows the pattern of electrodes exactly. In addition, the hydrogel's height is controllable by applied potential and reaction time. An equivalent circuit model and a hydrogel growth model have been built to predict the electrodeposition current and hydrogel's growth. This method for gel formation is easy and cheap since the main material is one piece of insulated paper, which provides an easy and controllable method for 3D hydrogel patterning.

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Scleractinium Coral Aquaculture Skeleton: a Possible 3D Scaffold for Cell Cultures and Bone Tissue Engineering

Cited by 8 publications

References 7 publications

Synthetic and Marine-Derived Porous Scaffolds for Bone Tissue Engineering

Synthetic and Marine-Derived Porous Scaffolds for Bone Tissue Engineering

Synthetic and Marine-Derived Porous Bone Graft Substitutes

Paper-Based Electrodeposition Chip for 3D Alginate Hydrogel Formation

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