Scleral Ulceration Caused by Cryptococcus albidus in a Patient With Acquired Immune Deficiency Syndrome

Garelick, Jordan M.; Khodabakhsh, Afshin James; Lopez, Yineth; Bamji, Mahrukh; Lister, Mark

doi:10.1097/01.ico.0000126322.13143.7b

Cited by 26 publications

(16 citation statements)

References 4 publications

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“…The 2 (1%) isolates of Rhodotorula glutinis showed a range of 6-13 mm of zone diameter to both fluconazole and voriconazole, which is consistent with other studies. [30][31][32][33] The germ tube method used to confirm C. albicans in this study, although accepted for non-sterile site isolates, is not sufficiently accurate when confirming these isolates as misidentifications are a distinct possibility, e.g. C. dubliniensis isolates might be misidentified as C. albicans.…”

Section: Discussionmentioning

confidence: 99%

Antifungal susceptibility profile of yeast isolates from sterile sites at a tertiary hospital in South Africa

Makhado

Ismail

Dangor

et al. 2014

Southern African Journal of Infectious Diseases

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Section: Discussionmentioning

confidence: 99%

Antifungal susceptibility profile of yeast isolates from sterile sites at a tertiary hospital in South Africa

Makhado

Ismail

Dangor

et al. 2014

Southern African Journal of Infectious Diseases

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“…Ocular manifestations included deteriorating vision, painless scleral ulcer and corneal infiltrates [50][51][52][53]. Two patients receiving chronic ambulatory peritoneal dialysis had peritonitis [25,54,55].…”

Section: Other Body Site Infectionsmentioning

confidence: 99%

Non-neoformans Cryptococcal Infections: a Systematic Review

2007

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Non-neoformans cryptococci have been generally regarded as saprophytes and rarely reported as human pathogens. However, the incidence of infection due to these organisms has increased over the past 40 years, with Cryptococcus laurentii and Cryptococcus albidus, together, responsible for 80% of reported cases. Conditions associated with impaired cell-mediated immunity are important risks for non-neoformans cryptococcal infections and prior azole prophylaxis has been associated with antifungal resistance. The presence of invasive devices was a significant risk factor for Cryptococcus laurentii infection (adjusted OR = 8.7; 95% CI = 1.48-82.9; p = 0.003), while predictors for mortality included age > or =45 years (aOR = 8.4; 95% CI = 1.18-78.82; p = 0.004) and meningeal presentation (aOR = 7.0; 95% CI = 1.85-60.5; p= 0.04). Because clinical manifestations of non-neoformans cryptococcal infections are most often indistinguishable from Cryptococcus neoformans, a high index of suspicion remains important to facilitate early diagnosis and prompt treatment for such infections.

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“…To our knowledge, just 26 cases of infection with C. albidus have been reported in the world literature [ Table 1 (1,(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19)(20)(21)(22)(23)]. The present case is unusual both because peritonitis with C. albidus has never before been reported, and because cryptococcal peritonitis is in general very rare, with only 4 cases having been reported in patients on PD (24).…”

Section: Discussionmentioning

confidence: 69%

Case Report of Cryptococcus Albidus Peritonitis in a Peritoneal Dialysis Patient and a Review of the Literature

Ragupathi

Reyna

2015

Perit Dial Int

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Cryptococcus albidus is a saprophytic yeast linked to just 26 reports of human infection in the world literature. Here, we report the first case of C. albidus peritonitis, in a patient with end-stage renal disease and hepatitis C-associated cirrhosis who is on peritoneal dialysis. The patient was treated successfully with a week-long course of amphotericin B. Non-neoformans cryptococcal infections present a clinical challenge, because they are difficult to diagnose and lack established guidelines for treatment. We present a review of the literature on C. albidus infections and their treatment.

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Scleral Ulceration Caused by Cryptococcus albidus in a Patient With Acquired Immune Deficiency Syndrome

Abstract: Cryptococcus albidus rarely causes disease in humans. It should be considered as a potential cause of ocular and systemic disease in patients with AIDS.

Cited by 26 publications

References 4 publications

Antifungal susceptibility profile of yeast isolates from sterile sites at a tertiary hospital in South Africa

Antifungal susceptibility profile of yeast isolates from sterile sites at a tertiary hospital in South Africa

Non-neoformans Cryptococcal Infections: a Systematic Review

Case Report of Cryptococcus Albidus Peritonitis in a Peritoneal Dialysis Patient and a Review of the Literature

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