Scleredema of Buschke following <i>Mycoplasma pneumoniae</i> respiratory infection

Morais, Paulo; Almeida, Marta; Santos, P.; Azevedo, Filomena

doi:10.1111/j.1365-4632.2010.04513.x

Cited by 7 publications

(19 citation statements)

References 16 publications

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“…This subtype is more common in females and is found in all ages and races. Most cases are below 20 years of age [4, 5]. Type II constitutes around 25% of all cases and is generally progressive and associated with monoclonal gammopathy and multiple myeloma [4].…”

Section: Discussionmentioning

confidence: 99%

“…Most cases are below 20 years of age [4, 5]. Type II constitutes around 25% of all cases and is generally progressive and associated with monoclonal gammopathy and multiple myeloma [4]. Type III, also referred to as scleredema diabetocorum or diabetic scleredema, consists around 20% of cases and is a known, rare complication of uncontrolled diabetes mellitus [4, 5].…”

Section: Discussionmentioning

confidence: 99%

“…The treatment modalities for type II and type III is non specific. Various agents that have been tried for the treatment include steroids, methotrexate, cyclosporine, radiotherapy, prostaglandin E1, factor XIII, systemic photochemotherapy with psoralene and ultraviolet A (PUVA), high dose penicillin, d-penicillamine etc [4, 8]. …”

Section: Discussionmentioning

confidence: 99%

“…Scleroderma is a major cutaneous feature of systemic sclerosis and is typically characterized by pigmented, thickened skin with bilateral, symmetrical involvement and centripetal progression. Histopathologic study shows thin epidermis and thickened dermis with excessive collagen [4, 5, 7, 9]. Scleromyxedema is a papular, waxy, diffuse involvement of the skin of fingers, face, neck and arms.…”

Section: Discussionmentioning

confidence: 99%

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Scleredema-an uncommon cause of swelling in a child-a case report and review of the literature

2014

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BackgroundBody swelling in a child is a common symptom. Apart from systemic causes like renal, hepatic, and cardiac, rarely such a swelling may be caused by dermatologic conditions.Case presentationA child presented with swelling of the body which was subsequently diagnosed as scleredema, a rare and benign dermatologic condition. Scleredema can be confused with similar sounding terms like scleroderma and scleromyxedema.ConclusionsThe case is presented to highlight scleredema as a rare cause of body swelling in paediatrics and to differentiate it from similar sounding rare terms like scleroderma and scleromyxedema.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Scleredema-an uncommon cause of swelling in a child-a case report and review of the literature

2014

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“…Its exact prevalence and incidence are unknown. Three types of scleredema can been distinguished according to their association with preceding or underlying conditions: Type 1 (the classic ‘Buschke’ type, 55% of cases) usually follows a febrile infection (especially streptococcal or viral respiratory tract infection) and affects mainly children . Type 2 (25%) is associated with paraproteinemia including monoclonal gammopathy, multiple myeloma and amyloidosis .…”

Section: Scleredemamentioning

confidence: 99%

European dermatology forum S1-guideline on the diagnosis and treatment of sclerosing diseases of the skin, Part 2: Scleromyxedema, scleredema and nephrogenic systemic fibrosis

Knobler

Moinzadeh

Hunzelmann

et al. 2017

J Eur Acad Dermatol Venereol

119

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The term 'sclerosing diseases of the skin' comprises specific dermatological entities which have fibrotic changes of the skin in common. These diseases mostly manifest in different clinical subtypes according to cutaneous and extracutaneous involvement and can sometimes be difficult to distinguish from each other. The present guideline focuses on characteristic clinical and histopathological features, diagnostic scores and the serum autoantibodies most useful for differential diagnosis. In addition, current strategies in the first- and advanced-line therapy of sclerosing skin diseases are addressed in detail. Part 2 of this guideline provides clinicians with an overview of the diagnosis and treatment of scleromyxedema, scleredema (of Buschke) and nephrogenic systemic sclerosis (nephrogenic fibrosing dermopathy).

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Cutaneous Mucinoses

Rongioletti

2016

Rook's Textbook of Dermatology, Ninth Edition

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The cutaneous mucinoses are a heterogeneous group of disorders whose main characteristic is abnormal mucin deposition in the skin. The aetiopathogenesis of cutaneous mucinoses is unknown, although cytokines such as tumour necrosis factor α and β, interleukin 1, interleukin 6 and transforming growth factor β and/or polyclonal and monoclonal immunoglobulins and other unidentified factors in the serum of affected patients may induce up‐regulation of glycosaminoglycan synthesis. The cutaneous mucinoses are divided into two categories: (i) primary cutaneous mucinoses in which the mucin deposit is the main histological feature resulting in clinically distinctive lesions; and (ii) secondary mucinoses in which the mucin deposition is only an additional histological epiphenomenon. Primary mucinoses can be divided into dermal and follicular mucinoses. The former includes lichen myxoedematosus, reticular erythematous mucinosis, scleroedema, mucinoses in thyroid disease, papular and nodular mucinosis in connective tissue diseases, self‐healing juvenile cutaneous mucinosis, cutaneous focal mucinosis, digital myxoid cyst; the latter include Pinkus follicular mucinosis and urticaria‐like follicular mucinosis. Associated disorders include paraproteinaemia (scleromyxoedema, scleroedema), diabetes mellitus (scleroedema), hyperthyroidism (pretibial myxoedema), hypothyroidism (generalized myxoedema) and lupus erythematosus, dermatomyositis or scleroderma (papular and nodular mucinosis in connective tissue diseases).

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Scleredema of Buschke following Mycoplasma pneumoniae respiratory infection

Cited by 7 publications

References 16 publications

Scleredema-an uncommon cause of swelling in a child-a case report and review of the literature

Scleredema-an uncommon cause of swelling in a child-a case report and review of the literature

European dermatology forum S1-guideline on the diagnosis and treatment of sclerosing diseases of the skin, Part 2: Scleromyxedema, scleredema and nephrogenic systemic fibrosis

Cutaneous Mucinoses

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