Sclerochoroidal Calcification

Shields, Carol L.; Hasanreisoğlu, Murat; Saktanasate, Jarin; Shields, Patrick W.; Seibel, Ira; Shields, Jerry A.

doi:10.1097/iae.0000000000000450

Cited by 47 publications

(54 citation statements)

References 13 publications

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“…In the vast majority of cases, SCC is idiopathic but may be associated with secondary causes of hypercalcemia. Despite the benign nature of SCC, it can lead to atrophy of the overlying retinal pigment epithelium (RPE) and, rarely, secondary choroidal neovascularization, which can be vision-threatening [2]. Herein, we describe a case of choroidal neovascularization associated with SCC.…”

Section: Introductionmentioning

confidence: 99%

“…Clinically, it is characterized by yellow or yellow-white lesions in the postequatorial fundus, most often in the superotemporal quadrant, which commonly appear flat but can also be elevated, mimicking a choroidal tumor. The lesions may be single or multiple and are often bilateral [2,3]. B-scan ultrasonography demonstrating acoustic shadowing characteristic of calcification can help confirm the diagnosis.…”

Section: Introductionmentioning

confidence: 99%

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Multimodal Imaging of Choroidal Neovascularization Associated with Sclerochoroidal Calcification

Bessette

Singh²

2016

Ocul Oncol Pathol

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We report a case of a choroidal neovascular membrane (CNVM) associated with sclerochoroidal calcification (SCC). An asymptomatic, 72-year-old male was referred to our institution for yellow-white placoid retinal lesions of both eyes. B-scan ultrasonography confirmed the diagnosis of SCC, and indocyanine green angiography confirmed the presence of an associated CNVM. Due to enlargement of a hemorrhagic pigment epithelial detachment associated with the CNVM over the course of 7 months, the patient was treated with a series of bevacizumab injections followed by photodynamic therapy (PDT). Due to persistence of the CNVM following PDT, the lesion was finally treated with argon laser photocoagulation. We describe the clinical course of this rare complication of SCC.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Multimodal Imaging of Choroidal Neovascularization Associated with Sclerochoroidal Calcification

Bessette

Singh²

2016

Ocul Oncol Pathol

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“…[12] SCC can masquerade as various intraocular tumors and is frequently misdiagnosed as choroidal metastasis or choroidal osteoma. The confusion with choroidal osteoma stems from the presence of calcification within both tumors; however, the clinical features differ in that osteoma affects young patients whereas SCC affects the elderly.…”

Section: Introductionmentioning

confidence: 99%

“…[4] In contrast, SCC appears more often in the superotemporal equator as a nodular elevation with shadowing on OCT emanating from the sclera outward. [1]…”

Section: Introductionmentioning

confidence: 99%

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Stones, bones, groans, thrones, and psychiatric overtones: Systemic associations of sclerochoroidal calcification

et al. 2017

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Sclerochoroidal calcification (SCC) is a frequent masquerader of choroidal melanoma with important systemic associations such as hyperparathyroidism and parathyroid adenoma. Herein, we describe a case of a 67-year-old male who presented with an amelanotic choroidal lesion in the right eye (OD) and a history of kidney stones. Ultrasonography showed the lesion to be flat and calcified OD. Incidentally, a subclinical calcified plaque was also found in the fellow eye. Optical coherence tomography showed an elevated suprachoroidal mass in a table mountain configuration OD and flat configuration left eye, consistent with type 4 and type 1 SCC. The patient was referred for metabolic testing to rule out the underlying electrolyte imbalance and was found to be normal.

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Rare Complication of Sclerochoroidal Calcifications

2019

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A 75-year-old woman of white race/ethnicity was referred for bilateral choroidal lesions. She described her vision as being blurred in the left eye, with areas of her vision being "blocked." Her review of systems was unremarkable. Her medical and ocular histories were significant for pseudophakia of both eyes, obstructive sleep apnea, and hypertension treated with hydrochlorothiazide.On examination, visual acuity was 20/40 OD and 20/64 OS. Intraocular pressure, pupillary reaction, and ocular motility were normal. Confrontation visual fields revealed a deficit in the inferotemporal quadrant of the left eye. External and slitlamp examinations were unremarkable. Dilated fundus examination revealed an epiretinal membrane, as well as extramacular, elevated, hypopigmented, yellow lesions with retinal pigment epithelium changes in both eyes, along with overlying subretinal fluid, subretinal hemorrhage, and exudates in the left eye (Figure , A). Optical coherence tomography showed an epiretinal membrane with cystoid macular edema and drusen in both eyes, along with subretinal fluid extending into the left macula, explaining her decreased vision. B-scan ultrasonography demonstrated hyperechoic, plaquelike, solid lesions with posterior acoustic shadowing corresponding anatomically to the lesions seen on clinical examination (Figure , B). Fluorescein and indocyanine angiography demonstrated leakage in the area of subretinal hemorrhage in the left eye (Figure , C). Diagnosis Sclerochoroidal calcifications with secondary choroidal neovascularizationWhat to Do Next C. Check parathyroid hormone, vitamin D, and calcium levels Discussion

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Sclerochoroidal Calcification

Abstract: Sclerochoroidal calcification is a stable deposition of calcium in the sclera that, unlike choroidal osteoma, has minimal risk for vision loss. All patients with SCC should be evaluated for underlying systemic calcium disorders, especially parathyroid and renal metabolic conditions.

Cited by 47 publications

References 13 publications

Multimodal Imaging of Choroidal Neovascularization Associated with Sclerochoroidal Calcification

Multimodal Imaging of Choroidal Neovascularization Associated with Sclerochoroidal Calcification

Stones, bones, groans, thrones, and psychiatric overtones: Systemic associations of sclerochoroidal calcification

Rare Complication of Sclerochoroidal Calcifications

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