Scleromyxedema: A Case Report with Cutis-Laxa like Features

Abstract

Scleromyxedema is an uncommon disease that corresponds to the generalized form of lichen myxedematosus. It is clinically characterized by generalized papules with skin infiltration. Histopathology reveals a triad including mucin deposition, fibrosis and irregularly arranged fibroblastic proliferation. This disease presents multiple extracutaneous manifestations and is associated with other diseases, especially paraproteinemia. We present the case of a 75 year-old woman, who presented a scleromyxedema with cutis-laxa like features. These cutaneous changes are infrequently seen and have been recently described in the context of scleromyxedema.