Sclerosing Angiomatoid Nodular Transformation of the Spleen

Lee, Megan; Caserta, Melanie P.; Tchelepi, Hisham

doi:10.1097/ruq.0000000000000100

Cited by 5 publications

(3 citation statements)

References 9 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…1 ). Some articles describe the enhancement as a ‘spoke-wheel’ pattern, corresponding to a central, stellate fibrous stroma with fibrous septa separating angiomatoid nodules [ 3 8 9 10 11 12 13 14 15 ]. Morphologically SANT is lobulated in 59% (17/29) of cases and 31% (9/29) describe SANT as a lesion with smooth borders.…”

Section: Imaging Findingsmentioning

confidence: 99%

“…The sonographic characteristics of SANT was only mentioned in 14 articles. The most common presentation is a solitary heterogeneously hypoechoic mass [ 9 11 24 25 26 27 ]. Sporadic case reports have examined the possible utility of contrast-enhanced ultrasonography (CEUS) in the examination of SANT [ 11 25 26 27 ].…”

Section: Imaging Findingsmentioning

confidence: 99%

“…The most common presentation is a solitary heterogeneously hypoechoic mass [ 9 11 24 25 26 27 ]. Sporadic case reports have examined the possible utility of contrast-enhanced ultrasonography (CEUS) in the examination of SANT [ 11 25 26 27 ]. Gutzeit et al describes the enhancement of SANT on CEUS as a spoke-wheel pattern similar to the findings on multi-phase CT and MRI [ 25 ].…”

Section: Imaging Findingsmentioning

confidence: 99%

See 2 more Smart Citations

Sclerosing Angiomatoid Nodular Transformation of the Spleen: A Diagnostic Conundrum

Eede

Voorde

Vanhoenacker³

et al. 2022

Journal of the Belgian Society of Radiology

View full text Add to dashboard Cite

A splenic lesion often represents a diagnostic challenge due to relative scarcity and the broad differential diagnosis. Sclerosing Angiomatoid Nodular Transformation (SANT) of the spleen is usually encountered only incidentally. Although benign, patients with SANT often receive splenectomy, due to its rarity, diagnostic uncertainty and sometimes intimidating imaging morphology and size. Imaging features on computed tomography, magnetic resonance and positron emission tomography have a high diagnostic value for SANT and help differentiate this entity from other splenic lesions. When the imaging parameters are matched with core needle biopsy tissue analysis, further watchful waiting can be recommended in order to avoid splenectomy.

show abstract

Section: Imaging Findingsmentioning

confidence: 99%

Section: Imaging Findingsmentioning

confidence: 99%

Section: Imaging Findingsmentioning

confidence: 99%

See 1 more Smart Citation

Sclerosing Angiomatoid Nodular Transformation of the Spleen: A Diagnostic Conundrum

Eede

Voorde

Vanhoenacker³

et al. 2022

Journal of the Belgian Society of Radiology

View full text Add to dashboard Cite

show abstract

Sclerosing Angiomatoid Nodular Transformation of the Spleen: A Systematic Review

Trigui,

Toumi,

Bouzid

et al. 2024

Curr Surg Rep

View full text Add to dashboard Cite

Sclerosing angiomatoid nodular transformation presenting with thrombocytopenia after laparoscopic splenectomy - Case report and systematic review of 230 patients

Aziret

Yılmaz

Kalpakci

et al. 2020

Annals of Medicine and Surgery

View full text Add to dashboard Cite

Background Sclerosing angiomatoid vascular transformation (SANT) is a rare vascular disease of the spleen, which is difficult to diagnose due to its pre-intervention appearance of malignancy. Case Report: An 85-year-old male was transferred to our clinic for thrombocytopenia and splenic mass. A contrast enhanced abdominal CT and MRI showed nodular lesions, the largest 50mm in diameter, and several areas of heterogeneous contrast field involvement in the spleen parenchyma. Laparoscopic splenectomy was performed with normal range of platelet level. The patient's postoperative course was uneventful and he was discharged on the 6th postoperative day. Histopathology revealed SANT. The patient is now in the 18 th month of remission with platelet levels within normal range and with no recurrence. Results Between 2004 and April 2020, a total of 230 SANT patients who underwent laparoscopic or open splenectomy or biopsy were reported in the literature. Most patients were female (52.1%), and the median age was 46 years (9 weeks-85 years). Most patients were asymptomatic (56%). Open splenectomy was performed on 166 patients (72.1%),laparoscopic splenectomy on 35 patients (15.2%) and laparoscopic partial splenectomy on 15 patients (6.5%). The median operation time and spleen weight were 143 minutes (88-213) and 260gr (68-2,720), respectively. Median follow-up time was 12 months (0-166). No recurrence was seen in patients undergoing total splenectomy. Conclusion SANT is an unusual disease of the spleen. In the light of this systematic review, a minimally invasive method for total or partial splenectomy,specifically laparoscopy, can be preferred as the treatment of choice.

show abstract

Sclerosing Angiomatoid Nodular Transformation of the Spleen

Cited by 5 publications

References 9 publications

Sclerosing Angiomatoid Nodular Transformation of the Spleen: A Diagnostic Conundrum

Sclerosing Angiomatoid Nodular Transformation of the Spleen: A Diagnostic Conundrum

Sclerosing Angiomatoid Nodular Transformation of the Spleen: A Systematic Review

Sclerosing angiomatoid nodular transformation presenting with thrombocytopenia after laparoscopic splenectomy - Case report and systematic review of 230 patients

Contact Info

Product

Resources

About