Sclerosing cholangitis-like changes in hepatobiliary tuberculosis

Özın, Yasemin; Parlak, Erkan; Kılıç, Zeynep; Temuçin, Tülay; Şaşmaz, Nurgül

doi:10.4318/tjg.2010.0049

Cited by 5 publications

(5 citation statements)

References 4 publications

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“…TB involvement of the hepatobiliary tract may be isolated, associated with additional enteric involvement, or occur in the setting of miliary tuberculosis. It may manifest in a variety of ways including tuberculous pseudotumor [75], tuberculous cholangitis [76], tuberculous liver abscess [77], and tuberculous hepatitis [74]. Fulminant hepatic failure has been reported but is exceedingly rare [78].…”

Section: Hepatobiliarymentioning

confidence: 99%

Tuberculosis of the gastrointestinal tract and associated viscera

Malikowski

Mahmood

Smyrk

et al. 2018

Journal of Clinical Tuberculosis and Other Mycobacterial Diseas

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Tuberculosis involvement of the gastrointestinal tract, peritoneum, and associated viscera is an uncommon but well described entity. While peritoneal tuberculosis and tuberculous enteritis are more common, involvement of the esophagus, stomach, colon, rectum, anus, liver, bile ducts, gallbladder, and pancreas can occur. Diagnosis is challenging as cases often mimic neoplasm or inflammatory bowel disease. In this review we outline the pathogenesis, clinical presentation, diagnostic testing, and treatment strategies pertaining to such cases.

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Section: Hepatobiliarymentioning

confidence: 99%

Tuberculosis of the gastrointestinal tract and associated viscera

Malikowski

Mahmood

Smyrk

et al. 2018

Journal of Clinical Tuberculosis and Other Mycobacterial Diseas

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“…Hilar strictures in biliary TB are difficult to distinguish from cholangiocarcinoma, but the younger age (<40 years in two-thirds), history of low-grade fever before the onset of jaundice, presence of extra hepatic TB and calcifications in the liver are suggestive [72]. Brush cytology demonstrating acid-fast bacilli (AFB), biopsies showing caseating granulomas, and bile PCR for AFB are useful tests [71, 73, 74]. Hilar nodal disease and compression from granulomas may also cause ductal abnormalities on imaging.…”

Section: Infectivementioning

confidence: 99%

Klatskin-Like Lesions

Kumar

Marudanayagam

2012

HPB Surgery

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Hilar cholangiocarcinoma, also known as Klatskin tumour, is the commonest type of cholangiocarcinoma. It poses unique problems in the diagnosis and management because of its anatomical location. Curative surgery in the form of major hepatic resection entails significant morbidity. About 5–15% of specimens resected for presumed Klatskin tumour prove not to be cholangiocarcinomas. There are a number of inflammatory, infective, vascular, and other pathologies, which have overlapping clinical and radiological features with a Klatskin tumour, leading to misinterpretation. This paper aims to summarise the features of such Klatskin-like lesions that have been reported in surgical literature.

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“…Grossly, liver can show nodules (tuberculoma/tubercular abscess) which may mimick primary or metastatic malignancy [ 1 ]. Biliary involvement can lead to diffuse thickening or strictures resembling primary sclerosing cholangitis or cholangiocarcinoma [ 5 , 6 ]. In our case too, possibility of malignancy could not be ruled out on gross examination.…”

Section: Discussionmentioning

confidence: 99%

“…SSC aetiologies are various, including infection. In HBTB, SSC-like changes have been described on cholangiography [ 5 , 6 ]. However in our case, similar changes were seen on histology, which have not been previously described.…”

Section: Discussionmentioning

confidence: 99%

Secondary sclerosing cholangitis in localized hepatobiliary tuberculosis simulating cholangiocarcinoma: a rare case report

et al. 2017

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BackgroundHepatobiliary tuberculosis includes miliary, tuberculous hepatitis or localized forms. The localised form is extremely uncommon and can mimic malignancy. Still rarer is its presentation as sclerosing cholangitis.Case presentationA 50 year male presented with acute onset jaundice, significant weight loss and elevated liver enzymes with clinico-radiological suspicion of cholangiocarcinoma. A left hepatectomy was done and dilated bile ducts filled with caseous necrotic material were seen intra-operatively. Histopathology suggested localized hepatobiliary tuberculosis with features of secondary sclerosing cholangitis.ConclusionLocalised hepatobiliary tuberculosis can cause diagnostic difficulties and its possibility should be considered especially in endemic areas.

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Sclerosing cholangitis-like changes in hepatobiliary tuberculosis

Cited by 5 publications

References 4 publications

Tuberculosis of the gastrointestinal tract and associated viscera

Tuberculosis of the gastrointestinal tract and associated viscera

Klatskin-Like Lesions

Secondary sclerosing cholangitis in localized hepatobiliary tuberculosis simulating cholangiocarcinoma: a rare case report

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