Sclerosing Peritoneal Mesothelioma in a Dog – A Case Report

Geninet, C.; Bernex, Florence; Rakotovao, Farasoa; Crespeau, François; Parodi, André-Laurent; Fontaine, Jacques

doi:10.1046/j.0931-184x.2003.00566.x

Cited by 40 publications

(42 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Fluid accumulation is the major sign [6]. Many studies has been described that the complete blood count was normal [1,6,7] but in our case the patient has moderate leucocytosis. Compatible with our case remarkable leucocytosis (30.5  10 9 /L) was also found in a six year old male crossbred dog with pericardial mesothelioma.…”

Section: Discussionmentioning

confidence: 91%

“…The diagnosis of mesothelioma is based primarily on gross and microscopic appearance. Additional immunohistochemical and electron microscopic examinations may be applied to confirm the diagnosis [6]. The limitary of this report is that cytologic examination doesn't provide a definite diagnosis for mesothelioma.…”

Section: Discussionmentioning

confidence: 99%

“…In some studies and case reports, malignant mesotheliomas have been induced in dogs exposed to intratracheal instillation of crocidolite asbestos and cigarette smoke [2,4]. Although some studies have been revealed that canine mesotheliomas present clinically with peritoneal effusion, most mesotheliomas have seen with pleural or pericardial effusions [5,6]. The purpose of the present report is to describe a case of pleural mesothelioma in a dog which has not a contact with asbestos, large amount of pestisides and cigarette smoke.…”

mentioning

confidence: 98%

See 2 more Smart Citations

Pleural Effusion in a Dog with Mesothelioma

Ülgen¹,

Bakırel²,

KutayYıldız³

et al. 2015

JLS

View full text Add to dashboard Cite

In this case; mesothelioma was likely diagnosed in 7 years old male mix breed dog which was brought to Veterinary Research and Teaching Hospital of Istanbul University with complaints of general weakness and severe dyspnea. The dog had been misdiagnosed with faryngitis and hernia diaphragmatica before it was brought to our faculty clinic. Apparent abdominal respiration was inspected and supressed heart sounds, abnormal respiratory sounds and pleural rub were detected by auscultation of thorax. Radiographic examination and blood analysis were performed. Chest X-ray examination demonstrates both sided pleural effusion. Leukocytosis (WBC = 36.2  10 3 µL) was detected on blood count. By thoracocentesis, 40 mL fluid was drained and cytologic examination was performed. Numerous pleomorphic, atypical, multinuclear or multinucleolar mesothelial cells were observed and cytologic findings were pretty compatible with mesothelioma. The dog died before medication and the owner of the dog didn't give the confirmation for necropsy. In our clinical case we did not confirm any contact of the dog with asbestos or larger amount of pesticides, which are described as etiological factors of mesothelioma. As mesothelioma is a very rare health condition for dogs, it might be lead up to misdiagnosis.

show abstract

Section: Discussionmentioning

confidence: 91%

Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 98%

See 1 more Smart Citation

Pleural Effusion in a Dog with Mesothelioma

Ülgen¹,

Bakırel²,

KutayYıldız³

et al. 2015

JLS

View full text Add to dashboard Cite

show abstract

“…Estes achados comprovam que a lesão não tem característica proliferativa epitelial, e sim inflamatória granulomatosa (Fig. 5 e 6) (Geninet et al, 2003). É importante realizar o diagnóstico diferencial de tumor etmoidal enzoótico, que, embora tenha localização anatômica e aspecto macroscópico semelhantes à conidiobolomicose em ovinos, apresenta curso clínico mais prolongado e diferentes lesões microscópicas (McKinnon et al, 1982).…”

unclassified

Conidiobolomicose em ovinos: reavaliação de três casos previamente diagnosticados como tumor etimoidal enzoótico

Silva¹,

Ferreira²,

Souza³

et al. 2010

Arq. Bras. Med. Vet. Zootec.

View full text Add to dashboard Cite

“…In many such cases presumptive or even definitive diagnosis can be based on microscopic examination of cellular samples (clinical cytology or cytopathology) collected during diagnostic procedures. However, in some cases cytology is insufficient and final diagnosis requires direct inspection of the affected cavity during laparotomy or thoracotomy, usually associated with collection of tissue samples for histopathological examination (Sisson et al 1984, Stępien et al 2000, Geninet et al 2003, Brisson et al 2006, Szczepulska-Wójcik et al 2007). …”

Section: Introductionmentioning

confidence: 99%

Cytomorphometry of serosal effusion in dogs

Przeździecki¹,

Czopowicz²,

Sapierzyński³

2015

Polish Journal of Veterinary Sciences

View full text Add to dashboard Cite

Cytomorphometry made on cytological slides is the quantitative method of precise analysis of cellular structures, including both cytoplasm and nucleus. The aim of this study was to describe cytomorphometric parameters of mesothelial cells in the course of benign reactive and malignant proliferation and to compare them to carcinomas and adenocarcinomas located within serosal cavities in dogs. The second aim was to evaluate applicability of cytomorphometry to diagnostics of diseases causing accumulation of effusion in serosal cavities. Cytological samples of normal and non-malignant mesothelium, mesothelioma and various carcinomas were collected from dogs. Cytomorphometry was made on the smears stained with Giemsa solution. Mean nuclear and cellular perimeter, mean nuclear and cellular area, mean nuclear and cellular diameter, and mean nuclear and cellular roundness were determined. Moreover, nuclear to cytoplasmic ratio (N/C) was calculated. The data revealed statistically significant differences for all parameters, excluding mean nuclear perimeter, between compared groups. Normal mesothelium cells and their nuclei were significantly smaller and more elongated than cells and nuclei of both benign reactive and malignant neoplastic mesothelium. Only a few differences were observed between benign reactive mesothelium cells and mesothelioma cells -mean nuclear area and mean nuclear diameter of benign reactive mesothelium cells were significantly larger and N/C ratio was higher in comparison to mesothelioma cells. Even though some significant differences were observed, considerable overlap of these cytomorphometric parameters in animals with different diseases limited practical role of these observations. Cytomorphometric analysis of cellular samples collected from dogs with proliferative processes affecting serosal cavities can be only an auxiliary method increasing accuracy of preoperative diagnosis.

show abstract

Sclerosing Peritoneal Mesothelioma in a Dog – A Case Report

Cited by 40 publications

References 7 publications

Pleural Effusion in a Dog with Mesothelioma

Pleural Effusion in a Dog with Mesothelioma

Conidiobolomicose em ovinos: reavaliação de três casos previamente diagnosticados como tumor etimoidal enzoótico

Cytomorphometry of serosal effusion in dogs

Contact Info

Product

Resources

About