Sclerosing Sweat Duct Carcinoma of the Eyelid

Kodama, Tatsuo; Tane, Nobuhiro; Ohira, Akihiro; Maruyama, Riruke; Fukuyama, Junichiro

doi:10.1007/s10384-003-0006-2

Cited by 5 publications

(11 citation statements)

References 17 publications

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“…Review of the literature identified 92 patients fulfilling the inclusion criteria for this study in addition to our current patient, for a total of 93 patients with MAC. 2,3,5,8,9,11–69 Patient demographics and presenting characteristics are summarized in Table 1.…”

Section: Resultsmentioning

confidence: 99%

“…Additional interventions included simple re-excision (11/34, 32%) 2,5,11,15,24,29,40,57,66 with positive margins in 4 of 11 (36%) 5,24,66 of these cases and excision with frozen section clearance of margins (3/34, 9%). 2,5,40 Mohs micrographic surgery was performed in 13 of 34 (38%) 3,5,8,13,14,21,24,45,46,49 patients with known information. 3,13,24,49 Of these 13 cases, 2 were handled with a staged Mohs excision.…”

Section: Resultsmentioning

confidence: 99%

“…Eighty-six of 93 (92%) tumors originated in the periocular skin, most commonly in the eyebrow (26/86, 30%) 12–14,17,18,20,22,23,25–27,29,30,36,37,43,47,48,53,59–61,67 followed by the lower eyelid (20/86, 23%). 2,8,11,13,32,33,35,39,40,49,54,56,58,59,62 Fifteen of 86 (17%) tumors involved more than 1 region. Primary orbital/periorbital involvement at presentation was reported in 11 of 86 (13%) patients, associated with diplopia in 3 patients.…”

Section: Resultsmentioning

confidence: 99%

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Periocular Microcystic Adnexal Carcinoma: A Case Report and a Major Review

Cheung

Rabinowitz

Tuluc

et al. 2023

Ophthalmic Plastic &Amp; Reconstructive Surgery

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Purpose: To describe a patient with periocular microcystic adnexal carcinoma (MAC) and to review the clinical presentation, systemic work-up, histopathologic features, and outcome of all previously reported periocular MAC. Methods: A major literature review. PubMed/MEDLINE and Google Scholar databases were searched for all well-documented cases of periocular MAC. Results: The final analysis yielded 93 patients with MAC, 48 (52%) females, 39 (42%) males, and 6 with sex not specified (6%) with an average age of 56 years (range 3 days–95 years). Most tumors were localized to the eyebrow (26/93, 28%) and lower eyelid (20/93, 22%). Of patients with known information, MAC most commonly presented as a nodule (37/68, 54%) or plaque (20/68, 29%) with poorly-defined margins (20/51, 39%) and distortion of eyelid margin (13/51, 25%). Orbital involvement at any point of the disease course was seen in 20 of 93 (22%) patients. An accurate histopathologic diagnosis on initial biopsy was made in 25 of 70 (36%) cases. Initial management included surgical excision (47/93, 51%), Mohs micrographic surgery (17/93, 18%), and excision with frozen section control of margins (8/93, 9%). Aggressive or recurrent MAC was managed with multimodal therapies, including adjuvant radiation (10/34, 29%). The average follow-up after the last treatment was 3 years (median 2, range 0.2–20 years). In total, 33 of 86 (38%) tumors recurred, and 6 of 87 (7%) metastasized. Disease-related mortality occurred in 3 of 79 (4%) of patients. Conclusions: Periocular MAC is frequently misdiagnosed on initial biopsy and has a tendency for recurrence and locally aggressive behavior, highlighting the importance of accurate timely diagnosis, and appropriate management.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Periocular Microcystic Adnexal Carcinoma: A Case Report and a Major Review

Cheung

Rabinowitz

Tuluc

et al. 2023

Ophthalmic Plastic &Amp; Reconstructive Surgery

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“…Most frequently madarosis is observed in patients with leprosy, where it has been reported in 27–76% of cases (Hogeweg & Leiker 1983; Soshamma & Surayawanshi 1989; Dana et al 1994; Cakiner & Karacorlu 1998; John & Daniel 1999). Madarosis is also frequently found in patients with malignomas or as paraneoplastic syndrome (Leib et al 1991; Saghari et al 2002; Kodama et al 2004). Further frequent causes of madarosis are endocrinological disorders or intoxications (Roy 1997).…”

Section: Discussionmentioning

confidence: 99%

Madarosis from mitochondriopathy

Finsterer

Brunner

2005

Acta Ophthalmologica Scandinavica

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“…[1111–113119120] A sebaceous cell carcinoma very often presents as a recurrent chalazion. An associated madarosis (due to lid infiltration and follicle destruction) would help to differentiate the two.…”

Section: Toxicitymentioning

confidence: 99%

Madarosis: A marker of many Maladies

Kumar

Karthikeyan

2012

Int J Trichol

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Madarosis is a terminology that refers to loss of eyebrows or eyelashes. This clinical sign occurs in various diseases ranging from local dermatological disorders to complex systemic diseases. Madarosis can be scarring or non-scarring depending upon the etiology. Appropriate diagnosis is essential for management. Follicular unit transplantation has been found to be a useful method of treating scarring madarosis and the procedure relevant to eyebrow and eyelash reconstruction has been discussed. A useful clinical approach to madarosis has also been included for bedside diagnosis. The literature search was conducted with Pubmed, Medline, and Google scholar using the keywords madarosis, eyebrow loss, and eyelash loss for articles from 1960 to September 2011. Relevant material was also searched in textbooks and used wherever appropriate.

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Sclerosing Sweat Duct Carcinoma of the Eyelid

Abstract: This tumor is seldom recognized and is frequently confused with benign syringoma or inflammation. Wide and deep excisional biopsy is necessary for correct diagnosis and successful treatment.

Cited by 5 publications

References 17 publications

Periocular Microcystic Adnexal Carcinoma: A Case Report and a Major Review

Periocular Microcystic Adnexal Carcinoma: A Case Report and a Major Review

Madarosis from mitochondriopathy

Madarosis: A marker of many Maladies

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