Furnace temperature (T), draw tension (TE), and draw ratio (Dr) are the main parameters that could directly affect holey polymer fiber (HPF) production during the drawing stage. Therefore, a suitable mechanism to control (T), (TE), and (Dr) is required to enhance the HPF production process. The conventional approaches, such as observation and tuning technique, experience many difficulties in realizing the accurate values of (T), (TE), and (Dr) in addition to being expensive and time consuming. Therefore, an artificial intelligence model using the adaptive neuro-fuzzy system (ANFIS) method is proposed as an effective solution to achieve an accurate value of the main parameters that affect HPF drawing. Three ANFIS models are developed and tested to determine which one has the best performance for emulating the operation of HPF drawing tower. The ANFIS model with a gbell MF provides a better performance than Gaussian MF ANFIS model and triangular MF ANFIS model in terms of lower mean absolute error and mean square error. Furthermore, the proposed gbell MF model achieved the highest Q–Q response, which indicates the excellent performance of this model.