ASVCPGuidelines: Principles of Quality Assurance and Standards for Veterinary Clinical Pathology (version 3.0)

Abstract

Resources:https://www.cms.gov/Regulations-and-Guidance/Legislation/CLIA/index.html CLIA summary https://wwwn.cdc.gov/clia CLIA website www.clsi.org Clinical Laboratory Standards Institute www.agriculture.gov.au/animal/health/system/lab-network#standards-and-accreditation and www.nata.com.au Information on Australia's accreditation system for veterinary laboratories www.iso.org International Organization for Standardization https://www.iso.org/standard/56115.html ISO's international standard 15189: Medical laboratories -Requirements for quality and competence www.ifcc.org

A comparison study between the results of the Siemens ADVIA 120 analyzer and the manual method for differential leukocyte counts in sheep

“…One limitation of our study is that the CBCs were not performed in duplicate as ideally recommended in the ASVCP guidelines for method comparison. 9 Another limitation is that the extremely low basophil numbers in our samples, although an expected finding in ruminants, precluded a meaningful comparison between the two methods. Finally, immature neutrophils and toxic changes were scarcely observed in only a few samples, and therefore, the possible effects of these cells on the A-Diff performance could not be assessed.…”

“…7 The following ex- guidelines for method comparison. 9 The statistical analyses were performed with the use of the statistical language R software program (R Foundation for Statistical Computing, Vienna, Austria).…”

Analytical performance and method comparison of a quantitative point-of-care immunoassay for measurement of bile acids in cats and dogs

“…The d obs % between control sample and sample spiked with interfering substances (hemoglobin, lipid, or bilirubin) should not exceed the TE a of 20%, 18 and a value less than 0.5 × TEa is desirable. 3…”

Effect of Age, Sex, and Breed on the Blood Biochemistry and Physiological Constants of Dogs From 4 Weeks to > 52 Weeks of Age.

“…Monitoring recommendations for clinical chemistry are addressed in the general American Society for Veterinary Clinical Pathology (ASVCP) quality assurance and laboratory standards guidelines (25,26). We evaluated the functioning of the analytical instrument with calibration curves for each blood analyte in GraphPad Prism version 6 (GraphPad Software, La Jolla, CA).…”

“…In addition, the spectrophotometer BTS-350 (BioSystems, Barcelona, Spain) has an internal quality control system based on the Levey-Jennings chart; this analysis allowed us to apply the Westgard rules. Before analyzing each determination, the analytical methods were calibrated according to the manufacturer's instructions with the help of a chemical calibrator and commercial controls (levels I and II) (Pointe Scienti c, Canton, MI) (25). Lipemic, hemolyzed, and icteric blood samples were excluded from the biochemical analysis (2).…”