<scp>B</scp>ritish<scp>A</scp>ssociation of<scp>D</scp>ermatologists' guidelines for the management of squamous cell carcinoma<i>in situ</i>(<scp>B</scp>owen's disease) 2014

Morton, C.A.; Birnie, Andrew; Eedy, D.J.; Hughes, Jenny; Sahota, A.; McDonagh, A.J.G.; Buckley, D.A.; Nasr, I.; Swale, V. J.; Williamson, C.E. Duarte; McHenry, P.; Levell, N. J.; Leslie, Tabi A.; Wagle, Shama; Towers, Kurt; Davis, Renée L.; Haveron, S.E.; Exton, L.S.; Mustapa, M.F. Mohd

doi:10.1111/bjd.12766

Cited by 170 publications

(136 citation statements)

References 170 publications

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“…For lesions on face, genital and digital lesions, Mohs surgery can be considered if feasible. (16) Curettage with cautery, less often used, is another simple economical modality of treatment. The success of it; however, depends on the skill of the performing physician.…”

Section: Discussion Of Managementmentioning

confidence: 99%

“…Pain and blistering and ulceration are common side effects. (16) Photodynamic therapy with 5-aminolevulinic acid (ALA) or methyl aminolevulinate (MAL) has very good clearance rates of 93% even with single cycle, comparable to curettage, cryotherapy and 5-FU. (13,15,17) From currently available data, it has high level of evidence for its use in BD.…”

Section: Discussion Of Managementmentioning

confidence: 99%

“…However, PDT is more efficacious in larger lesions. (15,16) This patient was started on topical 5-FU for the ease of topical therapy, since she was not willing for surgical methods of treatment. Newer modalities of treatment include topical diclofenac and lasers.…”

Section: Discussion Of Managementmentioning

confidence: 99%

See 2 more Smart Citations

Bowen’s Disease- A Case Report of a Rare Carcinoma in Situ

Mehta¹,

Priyadarshini²,

Rajesh³

et al. 2017

jemds

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Section: Discussion Of Managementmentioning

confidence: 99%

Section: Discussion Of Managementmentioning

confidence: 99%

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Bowen’s Disease- A Case Report of a Rare Carcinoma in Situ

Mehta¹,

Priyadarshini²,

Rajesh³

et al. 2017

jemds

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“…Neste contexto, a técnica de Karapandzic, é uma das opções mais versáteis, permitindo resultados cosméticos aceitáveis e preservação funcional. [6][7][8][9][10] CASO CLÍNICO Este trabalho reporta o caso de um homem de 71 anos referenciado por lesão do lábio inferior, ao nível da porção central e esquerda do vermelhão, hiperqueratósica, infiltrativa, com 3,5 cm de maior eixo e 1 ano de evolução, sugestiva de CEC (Fig. 1).…”

Section: Retalho De Karapandzic Uma Possível Solução Para Um Caso Deunclassified

“…O recurso a exames imagiológicos para despiste de invasão local ou à distância está, também, indicado em casos avançados, de modo a permitir o seu estadiamento e orientação. 10,11 Quanto ao tratamento, embora o elevado número de hipóteses terapêuticas ao dispor, a excisão cirúrgica continua a ser a primeira escolha, apresentando-se o retalho de Karanpadzic como uma opção válida para a reconstrução de grandes defeitos labiais, nomeadamente aqueles que ocupam 1/3 a 2/3 do comprimento do lábio inferior. As principais vantagens inerentes a esta técnica são, assim, a preservação da mobilidade e sensibilidade do lábio inferior, a preservação da continência oral, bem como a possibilidade de realização sob anestesia locorregional.…”

Section: Conclusãounclassified

Retalho de Karapandzic, uma Possível Solução para um Caso de Carcinoma Espinhocelular Avançado do Lábio

Abreu

Pinto-Gouveia

Brinca

et al. 2016

SPDV

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RESUMO -O carcinoma espinhocelular cutâneo é uma neoplasia cutânea não melanocítica, potencialmente fatal, que resulta da proliferação descontrolada dos queratinócitos. Predominante na cabeça e pescoço, esta surge preferencialmente em zonas expostas ao sol. O diagnóstico tem por base a apresentação clínica da lesão, corroborado com o auxílio da dermatoscopia, necessitando, porém, da confirmação histológica. Este trabalho reporta o caso de um homem de 71 anos referenciado por lesão do lábio inferior, hiperqueratósica e infiltrativa, sugestiva de carcinoma espinhocelular cutâneo. Confirmado a suspeita procedeu-se à excisão radical da lesão, cujo defeito resultante ocupava 70% do comprimento do lábio inferior na sua porção mediana, em espessura total, tendo-se recorrido à reconstrução com recurso aos retalhos de deslizamento e rotação descritos por Karapandzic. O resultado final caracterizou-se por cicatrizes a preencherem os sulcos fisiológicos e pela manutenção da continência oral, bem como da sensibilidade e mobilidade labiais. O CEC do lábio afeta principalmente adultos de raça caucasiana sujeitos a dose cumulativa elevada de radiação solar, registando-se um aumento da sua incidência ao longo das últimas décadas. 1,3,4 Além da exposição solar, a infeção por vírus do papiloma humano, o consumo de álcool, o tabagismo, a inflamação crónica, a imunossupressão, e síndromes genéticos como albinismo e xeroderma pigmentoso constituem igualmente fatores de risco. 1,4,5 Revista SPDV 74(2) 2016; Retalho de Karapandzic, uma solução para CEC do lábio;João Mendes-Abreu, Miguel Pinto-Gouveia, Ana Brinca, Ricardo Vieira. PALAVRAS-CHAVE -

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Assessment of Cutaneous Squamous Cell Carcinoma (cSCC) In situ Incidence and the Risk of Developing Invasive cSCC in Patients With Prior cSCC In situ vs the General Population in the Netherlands, 1989-2017

et al. 2020

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The incidence rates of keratinocyte cancer are increasing globally; however, the incidence rates of cutaneous squamous cell carcinoma (cSCC) in situ and the risk of developing subsequent invasive cSCC remain unknown. OBJECTIVE To estimate annual population-based age-standardized incidence rates of histopathologically confirmed cSCC in situ stratified by sex, age, and body site and to assess the risk of developing invasive cSCC among patients with cSCC in situ compared with the general population. DESIGN, SETTING, AND PARTICIPANTSThis nationwide epidemiological population-based cohort study used cancer registry data to identify all patients with a first incident of histopathologically confirmed cSCC in situ between January 1, 1989, and December 31, 2017. In addition, all patients with cSCC in situ who subsequently had a first incident of invasive cSCC were identified up to June 11, 2019. Data were analyzed between March 18 and November 12, 2019. MAIN OUTCOMES AND MEASURESAge-standardized incidence rates per year for cSCC in situ, standardized to the 2013 edition of the European Standard Population, were calculated by sex, age, and body site. Cumulative risks, standardized incidence ratios, and absolute excess risks were calculated to assess the risk of invasive cSCC in patients with cSCC in situ compared with the general population. RESULTSIn this population-based cohort study of 88 754 patients with a first incident of cSCC in situ between January 1, 1989, and December 31, 2017, 58.8% were women; the median age was 75 years (interquartile range [IQR], 67-82 years) for women and 73 years (IQR, 65-80 years) for men. Increasing incidence rates were observed, with the highest incidence rates in 2017 among women in general (71.7 cases per 100 000 person-years) and among men 80 years and older (540.9 cases per 100 000 person-years). The most common body site among women was the face (15.9 cases per 100 000 person-years) and among men was the scalp and/or neck (12.3 cases per 100 000 person-years). After 5 years of follow-up, among patients with cSCC in situ, the cumulative risk of developing an invasive cSCC at any anatomic location was 11.7% (95% CI, 11.6%-11.9%) in men and 6.9% (95% CI, 6.8%-7.0%) in women (P < .001). The standardized incidence ratio was highest in the first year of follow-up among both men (16.6; 95% CI, 15.7-17.5) and women (15.1; 95% CI, 14.2-16.1). CONCLUSIONS AND RELEVANCEThis study reports the first nationwide incidence rates of cSCC in situ to date. The increasing incidence rates of cSCC in situ and the high risk of developing invasive cSCC among patients with cSCC in situ may increase the health care burden associated with precursors of keratinocyte cancer and highlight the need to include cutaneous skin cancer precursor lesions when exploring policies to address skin cancer care.

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BritishAssociation ofDermatologists' guidelines for the management of squamous cell carcinomain situ(Bowen's disease) 2014

Cited by 170 publications

References 170 publications

Bowen’s Disease- A Case Report of a Rare Carcinoma in Situ

Bowen’s Disease- A Case Report of a Rare Carcinoma in Situ

Retalho de Karapandzic, uma Possível Solução para um Caso de Carcinoma Espinhocelular Avançado do Lábio

Assessment of Cutaneous Squamous Cell Carcinoma (cSCC) In situ Incidence and the Risk of Developing Invasive cSCC in Patients With Prior cSCC In situ vs the General Population in the Netherlands, 1989-2017

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