CD34+ cell yield among healthy donors: Large‐scale model development and validation
Abdullah Alswied,
David Daniel,
Leonard N. Chen
et al.
Abstract:BackgroundSuccessful engraftment in hematopoietic stem cell transplantation necessitates the collection of an adequate dose of CD34+ cells. Thus, the precise estimation of CD34+ cells harvested via apheresis is critical. Current CD34+ cell yield prediction models have limited reproducibility. This study aims to develop a more reliable and universally applicable model by utilizing a large dataset, enhancing yield predictions, optimizing the collection process, and improving clinical outcomes.Materials and Metho… Show more
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