<scp>COVID</scp>‐19 policy measures—Advocating for the inclusion of the social determinants of health in modelling and decision making

Rangel, J. Cristian; Ranade, Sudit; Sutcliffe, Penny; Mykhalovskiy, Eric; Gastaldo, Denise; Eakin, Joan M.

doi:10.1111/jep.13436

Cited by 28 publications

(29 citation statements)

References 19 publications

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“…During the pandemic, people (especially those with COVID‐19) may experience stress, anxiety, depression, irritability, frustration, and hopelessness (Guo et al., 2020; Serafini et al., 2020). Such mental health concerns may lead to both shorter‐ and longer‐term problems, particularly when experienced in combination with other factors such as poverty and insufficient healthcare services (Rangel et al., 2020). Data from disasters suggest emotional distress as a prevalent phenomenon in directly affected and vulnerable populations (North & Pfefferbaum, 2013).…”

Section: Introductionmentioning

confidence: 99%

A mediating role for mental health in associations between COVID‐19‐related self‐stigma, PTSD, quality of life, and insomnia among patients recovered from COVID‐19

et al. 2021

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Introduction Patients with COVID‐19 often suffer from psychological problems such as post‐traumatic stress disorder (PTSD) and self‐stigmatization that may negatively impact their quality of life and sleep. This study examined mental health as a potential mediating factor linking self‐stigmatization and PTSD to quality of life and sleep. Methods Using a cross‐sectional design, 844 people who had recovered from COVID‐19 were called and interviewed. Data were collected using structured scales. Structural equation modeling was applied to assess fitness of a mediation model including self‐stigma and PTSD as independent factors and quality of life and insomnia as dependent variables. Results Mental health, COVID‐19‐related self‐stigma, and mental quality of life were associated. Insomnia, PTSD, and COVID‐19‐related self‐stigma displayed significant direct associations (r = .334 to 0.454; p < .01). A mediation model indicated satisfactory goodness of fit (CFI = 0.968, TLI = 0.950, SRMR = 0.071, RMSEA = 0.068). Mental health as a mediator had negative relationships with COVID‐19‐related self‐stigma, PTSD, and insomnia and positive associations with quality of life. Conclusion Mental health may mediate effects of COVID‐19‐related self‐stigma and PTSD on quality of life and insomnia. Designing programs to improve mental health among patients with COVID‐19 may include efforts to reduce negative effects of PTSD and COVID‐19‐related self‐stigma on quality of life and insomnia.

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Section: Introductionmentioning

confidence: 99%

A mediating role for mental health in associations between COVID‐19‐related self‐stigma, PTSD, quality of life, and insomnia among patients recovered from COVID‐19

et al. 2021

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“…A recent literature search for the period of 1 January 2020 to 30 December 2020 for the impacts of SDOH on COVID-19 resulted in 8417 unique articles. Some of these studies elaborately discuss the association between SDOH and COVID-19 in the context of population health [ 53 , 54 , 55 , 56 , 57 ]. SDOH related differential consequences of COVID-19 can be due to differential exposure and differential susceptibility to this virus [ 53 , 54 , 58 ].…”

Section: Population-specific Risk Factors and Comorbidities Leadimentioning

confidence: 99%

Therapeutic Intervention of COVID-19 by Natural Products: A Population-Specific Survey Directed Approach

et al. 2021

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To date very few promising leads from natural products (NP) secondary metabolites with antiviral and immunomodulatory properties have been identified for promising/potential intervention for COVID-19. Using in-silico docking studies and genome based various molecular targets, and their in vitro anti-SARS CoV-2 activities against whole cell and/or selected protein targets, we select a few compounds of interest, which can be used as potential leads to counteract effects of uncontrolled innate immune responses, in particular those related to the cytokine storm. A critical factor for prevention and treatment of SARS-CoV-2 infection relates to factors independent of viral infection or host response. They include population-related variables such as concurrent comorbidities and genetic factors critically relevant to COVID-19 health disparities. We discuss population risk factors related to SARS-CoV-2. In addition, we focus on virulence related to glucose-6-phosphate dehydrogenase deficiency (G6PDd), the most common human enzymopathy. Review of data on the response of individuals and communities with high prevalence of G6PDd to NP, prompts us to propose the rationale for a population-specific management approach to rationalize design of therapeutic interventions of SARS-CoV-2 infection, based on use of NP. This strategy may lead to personalized approaches and improve disease-related outcomes.

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“…It is surprising then that their limitations and the direct and collateral effects on equity in healthcare and socio‐economic life were not fully considered for the mathematical modelling that served as the “scientific” evidence to push for radical measures of social control. As argued elsewhere, 48 this vacuum did not allow for an informed public debate on the long‐term costs and benefits of the measures vis‐à‐vis the mathematical models projecting COVID‐19 deaths, which made the medical and ultimately the moral case for lockdowns. For example, reputable medical historians have pointed out, while in the short‐term quarantines and “lockdown” policies can be effective to manage viral outbreaks, they are unsustainable when extended over long periods of time.…”

Section: Assessing the Sustainability And Equity Of Social Control Mementioning

confidence: 99%

COVID‐19 policy measures—Advocating for the inclusion of the social determinants of health in modelling and decision making

Cited by 28 publications

References 19 publications

A mediating role for mental health in associations between COVID‐19‐related self‐stigma, PTSD, quality of life, and insomnia among patients recovered from COVID‐19

A mediating role for mental health in associations between COVID‐19‐related self‐stigma, PTSD, quality of life, and insomnia among patients recovered from COVID‐19

Therapeutic Intervention of COVID-19 by Natural Products: A Population-Specific Survey Directed Approach

A way forward: Considering the sustainability, equity and unintended effects of social control measures as a response to the COVID‐19 crisis

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