2021
DOI: 10.1002/mdc3.13239
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DUOGLOBE: One‐Year Outcomes in a Real‐World Study of Levodopa Carbidopa Intestinal Gel for Parkinson's Disease

Abstract: Background Levodopa‐carbidopa intestinal gel (LCIG) is an established treatment for improving motor and some non‐motor symptoms (NMS) in patients with advanced Parkinson's disease (PD). Prospective long‐term data in routine clinical practice are limited. Objective Assess LCIG effectiveness and safety in patients with advanced PD after 12 months during real‐world routine clinical practice. Methods Duodopa/Duopa in patients with advanced Parkinson's disease—a global observational study evaluating long‐term effec… Show more

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Cited by 29 publications
(33 citation statements)
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“…As reported previously [ 20 ], mean (standard deviation) scores on the PDQ-8 questionnaire were significantly improved from baseline to month 12 (–9.0±21.6; p < 0.001). Correlations between baseline parameters and improvements in PDQ-8 questionnaire scores were statistically significant, though weak.…”
Section: Resultssupporting
confidence: 84%
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“…As reported previously [ 20 ], mean (standard deviation) scores on the PDQ-8 questionnaire were significantly improved from baseline to month 12 (–9.0±21.6; p < 0.001). Correlations between baseline parameters and improvements in PDQ-8 questionnaire scores were statistically significant, though weak.…”
Section: Resultssupporting
confidence: 84%
“…A total of 195 patients, with a mean (standard deviation) age of 70.2 (8.2) years and a mean 11.2 (4.8) years since diagnosis, were enrolled in the study. Baseline characteristics and patient demographics were reported previously [ 20 ], and are summarized in Table 1 .…”
Section: Resultsmentioning
confidence: 99%
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