Abstract:Streptococcus salivarius, the most predominant human oral microbiota, is rarely associated with neonatal sepsis. This report aims to describe a rare culture‐proven case of early‐onset sepsis in a 3‐day‐old boy with isolated high‐grade fever. Streptococcus salivarius was isolated in two consecutive hemocultures and unexpectedly resistant to the conventional empirical antibiotics.
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