<scp>EQ</scp>‐5<scp>D</scp>‐derived health utility values in patients undergoing surgery for chronic rhinosinusitis

Remenschneider, Aaron K.; Scangas, George A.; Meier, Josh; Gray, Stacey T.; Holbrook, Eric H.; Gliklich, Richard E.; Metson, Ralph

doi:10.1002/lary.25054

Cited by 64 publications

(123 citation statements)

References 40 publications

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“…Whereas many studies report on the positive effects of nasal sinus surgery on patient's symptoms, quality of life and nasal endoscopy, which have been published in the past, only limited data is available on the effect of sinus surgery on olfaction . This is remarkable because olfaction is one of the major symptoms for diagnosis of CRS in international guidelines …”

Section: Introductionmentioning

confidence: 99%

Recovery of olfaction after sinus surgery for chronic rhinosinusitis: A review

Haxel

2019

The Laryngoscope

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Objective Investigation of the postoperative olfactory function after sinus surgery for chronic rhinosinusitis (CRS) with and without polyps in a review. Data Sources PubMed. Review Methods A comprehensive literature search was conducted through June 2018 using relevant keywords. The titles/abstracts were reviewed to identify studies evaluating the sense of smell in CRS‐patients pre‐ and postoperatively by either using the whole or parts of the University of Pennsylvania Smell Identification Test or the Sniffin’ Sticks test. Study characteristics and outcome data of the included studies were extracted. Results In total, 106 studies were retrieved. Twenty‐four studies comprising 1,956 patients were included after quality assessment. The number of patients investigated per study was 19 to 206. In the 24 studies, 959 patients with nasal polyps and 516 without nasal polyps were described. The follow‐up times varied between 0.5 and 28 months. Twenty‐three studies reported an improved sense of smell, at least in certain subgroups. An overall improvement was seen in approximately 50% of the included patients. Nasal polyposis and preoperative anosmia were associated with a higher chance of improvement in olfaction. In those studies that commented on deterioration after sinus surgery, a decrease in olfaction was found in a range from 0% to 10% of cases. Conclusion Olfaction can be improved by sinus surgery in about every second patient, especially if the patient had chronic rhinosinusitis with polyps, was anosmic, and had no prior surgery. A deterioration of sense of smell after surgery is rare. Laryngoscope, 129:1053–1059, 2019

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Section: Introductionmentioning

confidence: 99%

Recovery of olfaction after sinus surgery for chronic rhinosinusitis: A review

Haxel

2019

The Laryngoscope

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“…Understanding the outcomes, both in terms of potential benefits and harms, of ESS in the elderly will help optimize treatment selection in these patients . Furthermore, demonstrating the utility of costly interventions such as ESS in the aging population is becoming increasingly important to policy makers in a healthcare system with limited resources …”

Section: Discussionmentioning

confidence: 99%

“…In addition, no studies, to our knowledge, have explored the impact of age on ESS outcomes in regard to GHRQOL. Furthermore, demonstrating the utility of costly interventions such as ESS is becoming increasingly important to policy makers in a healthcare system with limited resources . Therefore, we sought to evaluate the impact of age on patient‐reported outcomes following ESS for CRS according to both sinonasal‐specific and GHRQOL metrics.…”

Section: Introductionmentioning

confidence: 99%

Impact of Age on Sinus Surgery Outcomes

et al. 2018

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Objectives/Hypothesis To evaluate the impact of age on patient‐reported quality of life (QOL) following endoscopic sinus surgery (ESS) for chronic rhinosinusitis (CRS). Study Design Prospective cohort study. Methods Six hundred thirty‐six patients with CRS were recruited from 11 otolaryngologic practices and completed the sinonasal‐specific, 22‐item Sino‐Nasal Outcome Test‐22 (SNOT‐22) and general health‐related EuroQol 5‐Dimension (EQ‐5D) questionnaires at baseline and 12 and 24 months after ESS. Patients were grouped chronologically to determine whether age at time of ESS was associated with clinical outcomes. Results Ages ranged from 18 to 80 years (mean ± standard deviation = 48.5 ± 14.4). Improvement was observed in postoperative SNOT‐22 scores at 12 and 24 months for all decades of life. Similar improvements were observed for EQ‐5D‐based health utility value (HUV) scores in all decades of life, except for the eldest cohort (ages 70–80, N = 33), who did not exceed the minimal clinically important difference at either 12 or 24 months following ESS. In regression analysis, age was not associated with sinonasal‐specific outcomes (change in SNOT‐22 scores) at 12 (P = .507) or 24 months (P = .955). In general health‐related outcomes, however, age was significantly associated with change in EQ‐5D‐based HUV scores from baseline to 12 months following ESS after adjusting for patient demographics, comorbidities, and surgical history (P = .049). Conclusions This study demonstrates that ESS for adult CRS sufferers offers improved QOL outcomes through the eighth decade of life. The impact of comorbidities on QOL needs to be carefully considered when assessing older patients for sinus surgery. Level of Evidence 2b Laryngoscope, 128:2681–2687, 2018

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“…Patient demographics, comorbidities, and preoperative computed tomography (CT) scores were recorded. This study represents a secondary analysis of a subset of patients enrolled in an ongoing prospective and previously reported study of QOL outcomes after ESS …”

Section: Methodsmentioning

confidence: 99%