Fe₃O₄@C@prNHSO₃H: A novel magnetically recoverable heterogeneous catalyst in green synthesis of diverse triazoles

Abstract

The core–shell magnetic nano‐catalyst of Fe3O4@C@PrNHSO3H was proposed, synthesized, and fully described by transmission electron microscopy, field‐emission scanning electron microscope, energy‐dispersive X‐ray, vibrating sample magnetometer, thermal gravimetric analysis, X‐ray diffraction, Fourier transform infrared, and X‐ray photoelectron spectroscopy analysis. Nontoxic texture, magnetic recovery capability, high thermal stability as well as low‐cost synthesis method were found as the unique features of the synthesized core–shell magnetic nano‐catalyst. Fe3O4@C@PrNHSO3H NPs were introduced as a modern magnetic heterogeneous catalyst in the solvent‐free synthesis of triazole derivatives through one‐pot, three‐component condensation of aldehyde, ammonium acetate, and nicotinic hydrazide. The pleasant yield of products, straightforward work‐up, mild reaction conditions, along with magnetically recoverable catalyst were enumerated as the most important advantages of the method. The Fe3O4@C@PrNHSO3H could be easily separated from the reaction mixture by an external magnet and reused six times with the desired catalytic activity.

Novel butane sulfonic acid-functionalized core–shell magnetic nanocatalysts for ultrasound-assisted coumarin synthesis

“…25,27,[31][32][33][34][35][36]41,45,46,48 In light of the aforementioned aspects, novel Fe 3 O 4 @C@PrNH@BuSO 3 H NPs were engineered and manufactured for the first time using a straightforward approach following our prior investigations. [41][42][43][44][45][46]49,50 Coumarins are heterocycles with a range of biological and therapeutic activities that can be found to be both naturally occurring and artificially synthesized. 51,52 Coumarin derivatives have received increasing attention due to their anti-HIV, antioxidant, anti-bacterial, anti-fungal, and anti-worm properties.…”

“…25,27,31–36,41,45,46,48 In light of the aforementioned aspects, novel Fe 3 O 4 @C@PrNH@BuSO 3 H NPs were engineered and manufactured for the first time using a straightforward approach following our prior investigations. 41–46,49,50…”

A CMC-g-poly(AA-co-AMPS)/Fe3O4 hydrogel nanocomposite as a novel biopolymer-based catalyst in the synthesis of 1,4-dihydropyridines

“…Due to the recent challenges, new protocols for efficiently synthesizing 1,4-DHP derivatives under environmentally safe conditions are still demanded. In continuation of our previous works on the synthesis and application of nanocatalysts in heterocyclic synthesis, 35–43 herein we wish to report the design, synthesis, and use of biopolymer-based CMC- g -poly(AA- co -AMPS)/Fe 3 O 4 hydrogel nanocomposites in the Hantzsch synthesis of 1,4-DHP derivatives under both thermal and ultrasound-assisted conditions (Scheme 1).…”