2023
DOI: 10.1111/jcmm.17847
|View full text |Cite
|
Sign up to set email alerts
|

GNG4, as a potential predictor of prognosis, is correlated with immune infiltrates in colon adenocarcinoma

Abstract: The tumour microenvironment (TME) and immunosuppression play an important role in colon cancer (CC) metastasis, which seriously affects the prognosis of CC. G protein subunit gamma 4 (GNG4) has been shown to participate in tumour progression and the tumour mutation burden (TMB) in colorectal cancer. However, the effect of GNG4 on the CC TME and immunology remains elusive. Weighted gene coexpression network analysis (WGCNA) was employed for screening aberrantly expressed genes associated with the immune score, … Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1

Citation Types

0
1
0

Year Published

2024
2024
2024
2024

Publication Types

Select...
2

Relationship

0
2

Authors

Journals

citations
Cited by 2 publications
(1 citation statement)
references
References 38 publications
0
1
0
Order By: Relevance
“…We therefore selected the IMvigor210 cohort including 348 urothelial carcinoma patients who received immunotherapy, which is the most widely used cohort of similar studies. [57][58][59] In the future, more research on TNBC immunotherapy responses and updates of related public databases will help to improve this issue. In addition, low ICD score group also had lower IC50 in some chemotherapy-targeted drugs, that is, higher drug sensitivity.…”
Section: Discussionmentioning
confidence: 99%
“…We therefore selected the IMvigor210 cohort including 348 urothelial carcinoma patients who received immunotherapy, which is the most widely used cohort of similar studies. [57][58][59] In the future, more research on TNBC immunotherapy responses and updates of related public databases will help to improve this issue. In addition, low ICD score group also had lower IC50 in some chemotherapy-targeted drugs, that is, higher drug sensitivity.…”
Section: Discussionmentioning
confidence: 99%