2014
DOI: 10.1111/iji.12117
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HLA‐A, HLA‐B and HLA‐DRB1 allele and haplotype diversity among volunteer bone marrow donors from Croatia

Abstract: The determination of human leucocyte antigen (HLA)-A, HLA-B and HLA-DRB1 alleles in the routine procedure of a volunteer hematopoietic stem cell (HSC) donor's registration in the Croatian Bone Marrow Donor Registry (CBMDR) is performed to enhance the odds of finding a suitable HLA compatible donor for patients in need of a HSC transplantation worldwide. However, besides its original purpose, it also provides valuable information about the HLA polymorphism among Croats. The aim of the present study was to analy… Show more

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Cited by 29 publications
(35 citation statements)
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“…We identified 24 HLA‐B allele groups in Albanians and 20 in Macedonian Muslims, and HLA‐B*51, HLA‐B*18 and HLA‐B*35 had frequency >10% in both groups. HLA‐B*51 is the most common also in Albanians, Bulgarians, Croatian and Greek (Grubic et al, ; Ivanova et al, ; Papassavas et al, ; Sulcebe et al, ), whilst in Bosnians and Turks the most common are HLA‐B*44 and HLA‐B*51 (Arnaiz‐Villena, Dimitroski, et al, ; Arnaiz‐Villena, Karin, et al, ; González‐Galarza et al, ). In the countries from West Europe and Russia, the most frequent allele groups are HLA‐B*44, HLA‐B*35, HLA‐B*08 and HLA‐B*07 (González‐Galarza et al, ).…”
Section: Resultsmentioning
confidence: 99%
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“…We identified 24 HLA‐B allele groups in Albanians and 20 in Macedonian Muslims, and HLA‐B*51, HLA‐B*18 and HLA‐B*35 had frequency >10% in both groups. HLA‐B*51 is the most common also in Albanians, Bulgarians, Croatian and Greek (Grubic et al, ; Ivanova et al, ; Papassavas et al, ; Sulcebe et al, ), whilst in Bosnians and Turks the most common are HLA‐B*44 and HLA‐B*51 (Arnaiz‐Villena, Dimitroski, et al, ; Arnaiz‐Villena, Karin, et al, ; González‐Galarza et al, ). In the countries from West Europe and Russia, the most frequent allele groups are HLA‐B*44, HLA‐B*35, HLA‐B*08 and HLA‐B*07 (González‐Galarza et al, ).…”
Section: Resultsmentioning
confidence: 99%
“…We identified 12 HLA‐DRB1 allele groups in Albanian and Macedonian Muslims (only HLA‐DRB1*09 was not detected), with HLA‐DRB1*11 (24.2%), HLA‐DRB1*13 (17.9%) and HLA‐DRB1*16 (10.9%) being the most common in Albanians, whereas in Macedonian Muslims the most common were HLA‐DRB1*11 (28.2%), HLA‐DRB1*16 (17.1%) and HLA‐DRB1*14 (17.1%). HLA‐DRB1*11 is the most common allele group in all populations on the Balkan Peninsula (Andric et al, ; A. Arnaiz‐Villena, Dimitroski, et al, ; Arnaiz‐Villena, Karin, et al, ; González‐Galarza et al, ; Grubic et al, ; Ivanova et al, ; Papassavas et al, ; Sulcebe et al, ; Vojvodić & Ademović‐Sazdanić, ). In the countries from West and North Europe, different profile of the allele groups in HLA‐DRB1 locus is present, with HLA‐DRB1*15, HLA‐DRB1*04 and HLA‐DRB1*07 being the most common (Dubois & Gebuhrer, ; González‐Galarza et al, ; Wennerström et al, ; Zahlavova et al, ), whilst in the South European population, the most frequent are HLA‐DRB1*11, HLA‐DRB1*07, HLA‐DRB1*13, HLA‐DRB1*04, HLA‐DRB1*03 and HLA‐DRB1*01 (González‐Galarza et al, ).…”
Section: Resultsmentioning
confidence: 99%
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“…Clinically, being acquainted with HLA distribution is a sine qua non for bone marrow donating centers [16], [17], forensic medicine [18], studies of HLA related disease such as type 2 diabetes [19], [20], [21] or multiple sclerosis [22], designing peptide vaccine and monoclonal antibodies against tumors [23], [24], infectious agents [25], [26], [27] and autoimmune disease [20], [28], as well as infertility treatment and assisted reproductive technologies [29], [30], [31].…”
Section: Introductionmentioning
confidence: 99%