2020
DOI: 10.1111/1759-7714.13628
|View full text |Cite
|
Sign up to set email alerts
|

EGF+61 A>G polymorphism does not predict response to first‐generation EGFR tyrosine kinase inhibitors in lung cancer patients

Abstract: Epidermal growth factor (EGF) and its receptor (EGFR) play a paramount role in lung carcinogenesis. The polymorphism in the EGF promoter region EGF +61A>G (rs4444903) has been associated with cancer susceptibility, but its role in lung cancer patients treated with tyrosine kinase inhibitors (TKIs) remains unknown. Here, we aimed to evaluate the predictive and prognostic role of EGF +61A>G SNP in lung cancer from Brazilian EGFR-mutated TKI-treated patients. Herein, patients carrying EGFR-sensitizing mutations s… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1

Citation Types

0
1
0

Year Published

2022
2022
2022
2022

Publication Types

Select...
2

Relationship

1
1

Authors

Journals

citations
Cited by 2 publications
(1 citation statement)
references
References 18 publications
0
1
0
Order By: Relevance
“…Nevertheless, our group has shown the association of genetic ancestry with important genetic alterations of lung cancer. 52,53…”
Section: Discussionmentioning
confidence: 99%
“…Nevertheless, our group has shown the association of genetic ancestry with important genetic alterations of lung cancer. 52,53…”
Section: Discussionmentioning
confidence: 99%