2021
DOI: 10.1111/bcp.15129
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Serenoa repens induced erectile dysfunction: Underdiagnosis and phytovigilance

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Cited by 5 publications
(4 citation statements)
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“…Our results are in agreement with previous reports, in which the combination of Se with lycopene and S. repens extract had a greater effect in decreasing prostate gland weight 14–16 . Nonetheless, adverse effects have been reported for the use of S. repens like those reported for finasteride such as erectile dysfunction 40 . Aging naturally increases OS, which is related to the pathophysiology of BPH.…”
Section: Discussionsupporting
confidence: 93%
See 1 more Smart Citation
“…Our results are in agreement with previous reports, in which the combination of Se with lycopene and S. repens extract had a greater effect in decreasing prostate gland weight 14–16 . Nonetheless, adverse effects have been reported for the use of S. repens like those reported for finasteride such as erectile dysfunction 40 . Aging naturally increases OS, which is related to the pathophysiology of BPH.…”
Section: Discussionsupporting
confidence: 93%
“… 14 , 15 , 16 Nonetheless, adverse effects have been reported for the use of S. repens like those reported for finasteride such as erectile dysfunction. 40 Aging naturally increases OS, which is related to the pathophysiology of BPH. The accumulated production of reactive oxygen species due to endogenous or exogenous causes, like testosterone, plays a determinant role in diseases such as BPH.…”
Section: Discussionmentioning
confidence: 99%
“…These results agree with previous reports, where the combination of pure lycopene, Se, and S. repens had a greater effect in decreasing prostate gland weight [ 14 , 15 ]. However, adverse effects have been reported for the use of S. repens like those reported for finasteride such as erectile dysfunction [ 18 ].…”
Section: Discussionmentioning
confidence: 99%
“…Most minor adverse effects are related to the gastrointestinal system, especially when taken on an empty stomach (European Medicines Agency, 2021; Laekeman & Vlietinck, 2013). Biological plausibility for the association of SR and gynecomastia (European Medicines Agency, 2021; Laekeman & Vlietinck, 2013) and erectile dysfunction (Gallo et al, 2022) have been described, and also cases of allergy have been reported (European Medicines Agency, 2021; Laekeman & Vlietinck, 2013). Increases in blood pressure and ocular effects have been listed in the summary of product characteristics (SPCs) of some marketed products (European Medicines Agency, 2021; Laekeman & Vlietinck, 2013).…”
Section: Introductionmentioning
confidence: 99%