miR‐31‐5p suppresses myocardial hypertrophy by targeting Nfatc2ip
Lamei Zhao,
Xiaotao Qian,
Zhenxing Ren
et al.
Abstract:Cardiac hypertrophy, worldwide known as an adaptive functional compensatory state of myocardial stress, is mainly believed to proceed to severe heart diseases, even to sudden death. Emerging studies have explored the microRNA alteration during hypertrophy. However, the mechanisms of microRNAs involved in cardiac hypertrophy are still uncertain. We studied young rats to establish abdominal aorta coarctation (AAC) for 4 weeks. With the significant downregulated cardiac function and upregulated hypertrophic bioma… Show more
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