2023
DOI: 10.1002/tox.23917
|View full text |Cite
|
Sign up to set email alerts
|

N6‐methyladenosine methylation regulator RBM15 promotes the progression of diabetic nephropathy by regulating cell proliferation, inflammation, oxidative stress, and pyroptosis through activating the AGE‐RAGE pathway

Abstract: BackgroundDiabetic nephropathy (DN) is a major cause of end‐stage renal disease throughout the world, and m6A modification plays a critical role in the progression of DN. We aimed to find m6A‐related genes and their regulatory mechanisms in DN.MethodsThe expression levels of four important m6A‐related genes (METTL16, RBM15, IGF2BP1, and ALKBH5) were detected by quantitative real‐time PCR (RT‐qPCR). RBM15 was chosen and its function was explored. The downstream pathway of RBM15 was screened by transcriptome seq… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...

Citation Types

0
0
0

Year Published

2024
2024
2025
2025

Publication Types

Select...
5

Relationship

0
5

Authors

Journals

citations
Cited by 6 publications
references
References 36 publications
0
0
0
Order By: Relevance