<scp>Post‐amputation</scp> pain: Comparing pain presentations between adults with and without increased <scp>amputated‐region</scp> sensitivity

Beisheim‐Ryan, Emma Haldane; Pohlig, Ryan T.; Hicks, Gregory E; Horne, John Robert; Sions, Jaclyn Megan

doi:10.1111/papr.13172

Cited by 2 publications

(3 citation statements)

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“…12 Phantom limb pain is the sensation of pain in the perceived missing limb and occurs in up to 95% of amputees. 2,[13][14][15] Although the exact pathogenesis of phantom pain is not fully understood, it is believed to be multifactorial with contributions from the peripheral and central nervous systems. 14 From a peripheral standpoint, the abnormal, spontaneous axonal activity, and inflammatory cytokines from neuromas are known to contribute to phantom limb pain.…”

Section: Introductionmentioning

confidence: 99%

“…Nearly 200,000 major amputations are performed in the United States each year, with many of these patients developing chronic postamputation pain. 1 , 2 Postamputation pain comprises residual limb pain and phantom limb pain. 2 Residual limb pain is pain at the site of amputation and can have multiple etiologies, including inflammation, infection, heterotopic ossification, and neuroma pain.…”

Section: Introductionmentioning

confidence: 99%

“… 1 , 2 Postamputation pain comprises residual limb pain and phantom limb pain. 2 Residual limb pain is pain at the site of amputation and can have multiple etiologies, including inflammation, infection, heterotopic ossification, and neuroma pain. 3 Neuroma pain is caused by instances in which regenerating nerves cannot reinnervate an end target and develop into a neuroma bulb consisting of aberrant free axons, fibrotic tissue, and blood vessels.…”

Section: Introductionmentioning

confidence: 99%

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Regenerative Peripheral Nerve Interface Surgery: Anatomic and Technical Guide

Leach

Dean

Kumar

et al. 2023

Plastic and Reconstructive Surgery - Global Open

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Summary: Regenerative peripheral nerve interface (RPNI) surgery has been demonstrated to be an effective tool as an interface for neuroprosthetics. Additionally, it has been shown to be a reproducible and reliable strategy for the active treatment and for prevention of neuromas. The purpose of this article is to provide a comprehensive review of RPNI surgery to demonstrate its simplicity and empower reconstructive surgeons to add this to their armamentarium. This article discusses the basic science of neuroma formation and prevention, as well as the theory of RPNI. An anatomic review and discussion of surgical technique for each level of amputation and considerations for other etiologies of traumatic neuromas are included. Lastly, the authors discuss the future of RPNI surgery and compare this with other active techniques for the treatment of neuromas.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Regenerative Peripheral Nerve Interface Surgery: Anatomic and Technical Guide

Leach

Dean

Kumar

et al. 2023

Plastic and Reconstructive Surgery - Global Open

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The problem of phantom pain

Strokan,

Оros,

Levchenko

2024

PNMP

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Background. Considering the military situation in Ukraine, the number of patients with mine-explosive injuries has increased significantly, as a result of which the number of amputees experiencing phantom pain has progressively increased. Effective treatment of pain in patients with mine-explosive injury, phantom pain is of crucial importance in the modern conditions of health care for prognostic improvement of quality and length of life, prevention of chronic pain, optimization of symptomatic treatment, socialization and rehabilitation of patients. Taking into account the internal political situation in the country, the number of amputees is increasing, therefore researching the ways of treatment and rehabilitation of people suffering from phantom limb pain is an urgent task. Purpose – to investigate the results of the effectiveness and safety of treatment of acute phantom pain in military personnel, taking into account the developed personalized treatment and rehabilitation measures. Materials and methods. The study involved patients with mine-explosive injuries, among whom the vast majority were military personnel, who received treatment according to the local protocol at the base of the «Feofania» hospital, the total number is not disclosed due to military secrecy. The number of subjects with phantom pain was 35.9% of the total number of wounded military patients. Results. Pain intensity, sleep quality, symptoms of anxiety and depression were evaluated using the visual analog scale (VAS), numerical rating scale (NRS) or pain drawing, neuropathic pain scale (the s-lanss pain score), phantom pain assessment scale (Limb deficiency and phantom limb questionnaire), Pittsburgh Sleep Quality Index (PSQI), pain anxiety symptom scale form 20, The hospital anxiety and depression scale (HADS), PHQ9. Conclusions. The problem is relevant, the protocols work, predictors of pain, constitutional features, mechanisms of pain and psychological state should be taken into account, which requires further study

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Post‐amputation pain: Comparing pain presentations between adults with and without increased amputated‐region sensitivity

Cited by 2 publications

References 54 publications

Regenerative Peripheral Nerve Interface Surgery: Anatomic and Technical Guide

Regenerative Peripheral Nerve Interface Surgery: Anatomic and Technical Guide

The problem of phantom pain

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