S ‐nitrosylation and thiolation

Abstract

Cysteine, one of the most reactive residues, is indispensable to the biological functions of many proteins. It constitutes the reactive centers of crucial enzymes and maintains protein confirmation of key cellular regulators. The posttranslational modifications of reactive cysteine residues, S‐nitrosylation and thiolation, have now emerged as evolutionally conserved fundamental cell signals in all species.