<scp>S</scp>urface, <scp>B</scp>iocompatible and <scp>H</scp>emocompatible <scp>P</scp>roperties of <scp>M</scp>eta‐<scp>A</scp>morphous <scp>T</scp>itanium <scp>O</scp>xide <scp>F</scp>ilm

Wang, Mao Sheng; Lee, Fei Peng; Shen, Yun-Dun; Chen, Chien Hsun; Ou, Keng Liang; Ou, Shih-Fu

doi:10.1111/ijac.12184

Cited by 6 publications

(2 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Among these, the new surface modification technology of micro-arc oxidation (MAO) can be used to grow TiO 2 -based rough and porous ceramic coating [ 23 , 24 ] and can dope the coating with bioactive elements, such as calcium and phosphate, by adjusting electrolyte composition to further enhance the blood compatibility of the implant. As reported by Wang et al [ 25 ] more Ca and P in the MAO-treated coating on Ti can improve the blood compatibility when compared with the MAO-treated coating containing small amounts of Ca and P. At present, further research is required on the use of MAO parameter optimization to build the surface microstructure of ultrafine-grained pure titanium and, thus, enhance the blood compatibility of the material.…”

Section: Introductionmentioning

confidence: 95%

Micro-Arc Oxidation Enhances the Blood Compatibility of Ultrafine-Grained Pure Titanium

Zhang

et al. 2017

Materials

View full text Add to dashboard Cite

Ultrafine-grained pure titanium prepared by equal-channel angular pressing has favorable mechanical performance and does not contain alloy elements that are toxic to the human body. It has potential clinical value in applications such as cardiac valve prostheses, vascular stents, and hip prostheses. To overcome the material’s inherent thrombogenicity, surface-coating modification is a crucial pathway to enhancing blood compatibility. An electrolyte solution of sodium silicate + sodium polyphosphate + calcium acetate and the micro-arc oxidation (MAO) technique were employed for in situ oxidation of an ultrafine-grained pure titanium surface. A porous coating with anatase- and rutile-phase TiO2 was generated and wettability and blood compatibility were examined. The results showed that, in comparison with ultrafine-grained pure titanium substrate, the MAO coating had a rougher surface, smaller contact angles for distilled water and higher surface energy. MAO modification effectively reduced the hemolysis rate; extended the dynamic coagulation time, prothrombin time (PT), and activated partial thromboplastin time (APTT); reduced the amount of platelet adhesion and the degree of deformation; and enhanced blood compatibility. In particular, the sample with an oxidation time of 9 min possessed the highest surface energy, largest PT and APTT values, smallest hemolysis rate, less platelet adhesion, a lesser degree of deformation, and more favorable blood compatibility. The MAO method can significantly enhance the blood compatibility of ultrafine-grained pure titanium, increasing its potential for practical applications.

show abstract

Section: Introductionmentioning

confidence: 95%

Micro-Arc Oxidation Enhances the Blood Compatibility of Ultrafine-Grained Pure Titanium

Zhang

et al. 2017

Materials

View full text Add to dashboard Cite

show abstract

“…It is well known that titanium possesses its excellent biocompatibility due to its very stable and corrosion resistant oxide layer [ 17 , 18 ]. TiO 2 layers have been considered a promising coating for implants with proven biocompatibility and blood compatibility [ 13 , 19 ].…”

Section: Resultsmentioning

confidence: 99%

Research of Electrosurgical Ablation with Antiadhesive Functionalization on Thermal and Histopathological Effects of Brain Tissues In Vivo

Hsiao

Kung

Chu

et al. 2014

BioMed Research International

Self Cite

View full text Add to dashboard Cite

Thermal injury and tissue sticking are two major concerns in the electrosurgery. In the present study, the effect of lateral thermal injury caused by different electrosurgical electrodes on wound healing was investigated. An electrosurgical unit equipped with untreated (SS) and titanium oxide layer-coated (TiO2-coated) stainless steel needle-type electrodes was used to create lesions on the rat brain tissue. TiO2 layers were produced by radiofrequency plasma and magnetron sputtering in the form of amorphous (TO-SS-1), anatase (TO-SS-2), and rutile (TO-SS-3) phase. Animals were sacrificed for evaluations at 0, 2, 7, and 28 days postoperatively. TO-SS-3 electrodes generated lower levels of sticking tissue, and the thermographs showed that the recorded highest temperature in brain tissue from the TO-SS-3 electrode was significantly lower than in the SS electrode. The total injury area of brain tissue caused by TO-SS-1 and TO-SS-3 electrodes was significantly lower than that caused by SS electrodes at each time point. The results of the present study reveal that the plating of electrodes with a TiO2 film with rutile phases is an efficient method for improving the performance of electrosurgical units and should benefit wound healing.

show abstract

Review of plasma electrolytic oxidation of titanium substrates: Mechanism, properties, applications and limitations

Aliofkhazraei

Macdonald

Matykina

et al. 2021

Applied Surface Science Advances

184

View full text Add to dashboard Cite

Surface, Biocompatible and Hemocompatible Properties of Meta‐Amorphous Titanium Oxide Film

Cited by 6 publications

References 24 publications

Micro-Arc Oxidation Enhances the Blood Compatibility of Ultrafine-Grained Pure Titanium

Micro-Arc Oxidation Enhances the Blood Compatibility of Ultrafine-Grained Pure Titanium

Research of Electrosurgical Ablation with Antiadhesive Functionalization on Thermal and Histopathological Effects of Brain Tissues In Vivo

Review of plasma electrolytic oxidation of titanium substrates: Mechanism, properties, applications and limitations

Contact Info

Product

Resources

About