Schools in Thailand are increasingly using tablet computers for active learning. As interactive technology is increasingly used in the classroom, teachers are becoming more concerned about it. This qualitative study explores using a tablet computer as an interactive tool for active learning in teaching science in English. The research study involved three classes with ninety-three Grade 8 students from a demonstration school in Southern Thailand. The study was carried out for three weeks in all three classes. The classroom implementation was recorded and analyzed. Ninety-five percent of the students used tablet computers for class participation, while five percent used phones. The results showed that students used their tablet computers to search for different body parts in English, words that described the body parts and the meaning of the words. They learned independently and at their own pace to complete the classroom tasks. The results suggested that tablet computers are an excellent interactive tool to support active learning in teaching science in English in Grade 8 classrooms.