Screening antimycobacterial activity of Baccharis dracunculifolia, Centella asiatica, Lantana camara and Pterodon emarginatus

Machado, Rachel Rocha Pinheiro; Dutra, Rafael C.; Pittella, Frederico; Raposo, Nádia Rezende Barbosa; Lesche, B.; Duarte, Rafael Silva; Soares, Geraldo Luiz Gonçalves; Kaplan, Maria Auxiliadora Coelho

doi:10.1590/1983-084x/14_148

Cited by 9 publications

(4 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Also, B. dracunculifolia leaf essential oil was reported to have antifungal action against Candida albicans (Pereira et al, 2011), fungal phytopathogens such as Rhizoctonia solani , Sclerotium rolfsii , and Sclerotinia minor (Fonseca et al, 2015), and antibacterial action against Mycobacterium sp. (Machado et al, 2015) and Streptococcus mutans (Pereira et al, 2016).…”

Section: Introductionmentioning

confidence: 99%

Antimicrobial Activity of Essential Oil of Baccharis dracunculifolia DC (Asteraceae) Aerial Parts at Flowering Period

et al. 2019

View full text Add to dashboard Cite

Baccharis dracunculifolia DC (Asteraceae) is a Brazilian native bush tree, and its leaf essential oil has been reported to possess some biological activities, but the antimicrobial activity of its aerial part essential oil at the flowering period is unknown or little studied, mainly against agents that cause foodborne diseases. Thus, this study aimed to determine the chemical composition and evaluate the antimicrobial activity of the essential oil of B. dracunculifolia aerial part at flowering period. This essential oil was obtained by hydro distillation and its chemical composition was determined by gas chromatography coupled with mass spectrometry (GC–MS). The minimum inhibitory concentration, minimum bactericidal concentration, and minimum fungicidal concentration of the essential oil were evaluated against eight bacteria and eight fungi using 96-well microtiter plates. The essential oil yield was 1.8 ± 0.07%, and spathulenol (27%) and trans-nerolidol (23%), both oxygenated sesquiterpenes, were the major compounds found among 30 chemical constituents identified. The essential oil presented bacteriostatic and bactericidal activities, mainly against Staphylococcus aureus, Bacillus cereus and Pseudomonas aeruginosa, and also fungistatic and fungicidal activities. However, its antibacterial activity was more effective than the antifungal one by using the essential oil at lower concentrations. Essential oil of B. dracunculifolia may be a potential alternative for food applications in order to reduce synthetic chemicals in a more sustainable food industry.

show abstract

Section: Introductionmentioning

confidence: 99%

Antimicrobial Activity of Essential Oil of Baccharis dracunculifolia DC (Asteraceae) Aerial Parts at Flowering Period

et al. 2019

View full text Add to dashboard Cite

show abstract

“…Segundo Machado et al (2015), o óleo essencial de B. dracunculifolia foi investigado contra espécies de Mycobacterium. De acordo com os produtos produzidos, o óleo não se apresentou como uma fonte promissora de drogas antimicobacterianas.…”

Section: Flavonoides Totais E Atividade Antioxidanteunclassified

Doseamento de Flavonoides e Avaliação da Atividade Antioxidante e Antimicrobiana de Baccharis Dracunculifolia DC de um Fragmento de Cerrado Sul-Mato-Grossense

Júnior

Silva²,

Moretti³

et al. 2022

Ensaios Ciênc.

View full text Add to dashboard Cite

A Baccharis dracunculifolia é utilizada como fitoterápica, e a própolis-verde, sintetizada pelas abelhas Apis mellifera a partir dessa apresenta princípios inflamatórios, antioxidantes e antimicrobianos. Este produto apícola é eficaz no combate a uma série de micro-organismos na medicina popular, logo, é fundamental o desenvolvimento de pesquisas que comprovem essas eficácias. Os objetivos do trabalho foram analisar o perfil microbiológico, dosear os flavonoides e verificar a atividade antioxidante da planta. As partes aéreas foram coletadas em um fragmento de cerrado sul-mato-grossense e processadas obtendo-se extratos com hexano, acetato de etila e etanol. Para análise microbiológica, a bactéria Staphylococcus aureus foi semeada em ágar e discos de filtro foram embebidos com os extratos e, junto com grupo controle, foram colocados em placas de Petri para posterior medição dos halos de inibição. Para doseamento dos flavonoides e avaliação da atividade antioxidante, folhas processadas foram levadas a Soxhlet para extração em metanol. Uma alíquota sofreu leitura em espectrofotômetro com diferentes concentrações de quercetina para construção de curva padrão. O ensaio antioxidante foi baseado no método de redução de radical e revelação utilizando DPPH. Como resultado, todos os extratos demonstraram inibição do crescimento bacteriano, indicando atividade antimicrobiana da planta. Também foi encontrado flavonoide com atividade antioxidante satisfatória. Levando em consideração que a B. dracunculifolia é empregada como planta medicinal, estudos como este podem corroborar com tal utilização, uma vez que a comprovação científica dos possíveis fitoterápicos é fundamental para a indústria farmacêutica e para os profissionais em saúde, colaborando com a evolução da medicina. Palavras-chave: Atividade Antimicrobiana. Atividade Antioxidante. Baccharis dracunculifolia. Flavonoides. Abstract Baccharis dracunculifolia is used as an herbal medicine, and green propolis, synthesized by Apis mellifera bees , has inflammatory, antioxidant and antimicrobial principles. This bee product is effective in combating a series of microorganisms in folk medicine, therefore it is essential to develop research to prove such effectiveness. The objectives of the study were to analyze the microbiological profile, dose the flavonoids and verify the plant's antioxidant activity. The aerial parts were collected in a fragment of cerrado sul-mato-grossense and processed, obtaining extracts with hexane, ethyl acetate and ethanol. For microbiological analysis, Staphylococcus aureus bacterium was seeded in agar and filter discs were soaked with the extracts and, together with the control group, were placed in Petri dishes for subsequent measurement of inhibition halos. To measure the flavonoids and evaluate the antioxidant activity, processed leaves were taken to Soxhlet for extraction in methanol. An aliquot was read in a spectrophotometer with different quercetin concentrations to build a standard curve. The antioxidant assay was based on the radical reduction and development method using DPPH. As a result, all the extracts showed bacterial growth inhibition, indicating the plant’s antimicrobial activity. Flavonoids with satisfactory antioxidant activity were also found. Taking into account that B. dracunculifolia is used as a medicinal plant, studies such as this one can corroborate with such use, since the scientific proof of possible herbal medicines is essential for the pharmaceutical industry and for health professionals, contributing to the medicine evolution. Keywords: Antimicrobial Activity. Antioxidant Activity. Baccharis dracunculifolia. Flavonoids.

show abstract

“…Lantana caatingensis showed inhibition values between 64 and over 1024 μg/mL against Gram-positive and 256–512 μg/mL against Gram-negative bacteria [ 16 ]. The species Lantana camara showed inhibition values between 64 and 256 mg/mL against Gram-positive and Gram-negative bacteria [ 26 ], and above 1250 μg/mL against Mycobacterium spp [ 83 ]. Lantana montevidensis showed inhibition at 256 μg/mL against Staphylococcus aureus and at 512 μg/mL against E. coli [ 27 ].…”

Section: Antimicrobial Activitymentioning

confidence: 99%

Antimicrobial Activity and Chemical Composition of Essential Oils from Verbenaceae Species Growing in South America

2018

View full text Add to dashboard Cite

The Verbenaceae family includes 2600 species grouped into 100 genera with a pantropical distribution. Many of them are important elements of the floras of warm-temperature and tropical regions of America. This family is known in folk medicine, and its species are used as digestive, carminative, antipyretic, antitussive, antiseptic, and healing agents. This review aims to collect information about the essential oils from the most reported species of the Verbenaceae family growing in South America, focusing on their chemical composition, antimicrobial activity, and synergism with commercial antimicrobials. The information gathered comprises the last twenty years of research within the South American region and is summarized taking into consideration the most representative species in terms of their essential oils. These species belong to Aloysia, Lantana, Lippia, Phyla, and Stachytarpheta genera, and the main essential oils they contain are monoterpenes and sesquiterpenes, such as β-caryophyllene, thymol, citral, 1,8-cineole, carvone, and limonene. These compounds have been found to possess antimicrobial activities. The synergism of these essential oils with antibiotics is being studied by several research groups. It constitutes a resource of interest for the potential use of combinations of essential oils and antibiotics in infection treatments.

show abstract

Screening antimycobacterial activity of Baccharis dracunculifolia, Centella asiatica, Lantana camara and Pterodon emarginatus

Cited by 9 publications

References 24 publications

Antimicrobial Activity of Essential Oil of Baccharis dracunculifolia DC (Asteraceae) Aerial Parts at Flowering Period

Antimicrobial Activity of Essential Oil of Baccharis dracunculifolia DC (Asteraceae) Aerial Parts at Flowering Period

Doseamento de Flavonoides e Avaliação da Atividade Antioxidante e Antimicrobiana de Baccharis Dracunculifolia DC de um Fragmento de Cerrado Sul-Mato-Grossense

Antimicrobial Activity and Chemical Composition of Essential Oils from Verbenaceae Species Growing in South America

Contact Info

Product

Resources

About