Screening for bipolar disorders: Clinical utilization of the Mood Disorders Questionnaire on an inpatient mood disorders unit

Improving the Screening Instrument of Bipolar Spectrum Disorders: Weighted Korean Version of the Mood Disorder Questionnaire

“…However, many studies have criticized MDQ’s usefulness and its discriminatory power for bipolar disorder 7,20–24). Additionally, some studies have suggested adjusting the cutoff value to enhance the instrument’s sensitivity 25,26)…”

Self‐report screening instruments differentiate bipolar disorder and borderline personality disorder

“…The original MDQ validation study in outpatient psychiatric clinics reported a sensitivity of 73% and specificity of 90% (Hirschfeld et al., 2000 ). Subsequent studies in a U.S.‐population‐based sample reported 28% sensitivity and 97% specificity (Hirschfeld et al., 2003 ), whereas the sensitivity was 92% and specificity 64% on an inpatient Mood Disorders Unit (Kung et al., 2015 )​. A meta‐analysis reported a sensitivity of 66% and specificity of 79% (Carvalho et al., 2015 ) in mental health settings and 43% sensitivity and 95% specificity in the Primary care or general population setting.…”

Screening for bipolar disorder with self-administered questionnaires: A critique of the concept and a call to stop publishing studies of their performance in psychiatric samples

“…This fundamental conceptual error in determining a cutoff score on bipolar disorder screening scales on the basis of optimal agreement with a diagnostic standard has continued in more recent studies. I reviewed 27 recently published studies that examined the performance of bipolar disorder screening scales across a range of scores (Bech, Christensen, Vinberg, Bech-Andersen, & Kessing, 2011;Boschloo et al, 2013;Chou et al, 2012;Cyprien et al, 2014;de Sousa Gurgel et al, 2012;Feng et al, 2016;Frey, Simpson, Wright, & Steiner, 2012;Gamma et al, 2013;Gan et al, 2012;Hsieh et al, 2016;Hu et al, 2012;Imamura et al, 2015;Kung et al, 2015;Leao & Del Porto, 2012;Lee et al, 2013Lee et al, , 2016Mosolov et al, 2014;Nallet et al, 2013;Pan & Yeh, 2015;Perugi et al, 2012;Poon, Chung, Tso, Chang, & Tang, 2012;Sasdelli et al, 2013;Smith et al, 2011;Waleeprakhon et al, 2014;Yang et al, 2014;Yang et al, 2011;Zaratiegui et al, 2011). Almost every study recommended a cutoff point on the screening scale that maximized or optimized the level of agreement with the diagnostic gold standard.…”