Screening for infectious diseases among unaccompanied minor refugees in Berlin, 2014–2015

Theuring, Stefanie; Friedrich-Jänicke, Barbara; Pörtner, Kirsten; Trebesch, Isabel; Durst, Anita; Dieckmann, Sebastian; Steiner, Florian; Harms, Gundel; Mockenhaupt, Frank P.

doi:10.1007/s10654-016-0187-x

Cited by 51 publications

(32 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The prevalence of both anaemia (5.2%) and iron deficiency (4.6%) was low compared to other Australian child refugee cohorts, and screening for hepatitis B, hepatitis C, schistosomiasis and faecal parasites in this cohort (no cases identified) perhaps warrants reappraisal if more Australian data are available to confirm our findings. Studies of Syrian refugees in Germany and Canada have also noted low prevalence of infectious diseases.…”

Section: Discussionmentioning

confidence: 99%

‘I think we've had a health screen’: New offshore screening, new refugee health guidelines, new Syrian and Iraqi cohorts: Recommendations, reality, results and review

Heenan

Volkman

Stokes

et al. 2018

J Paediatrics Child Health

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

‘I think we've had a health screen’: New offshore screening, new refugee health guidelines, new Syrian and Iraqi cohorts: Recommendations, reality, results and review

Heenan

Volkman

Stokes

et al. 2018

J Paediatrics Child Health

View full text Add to dashboard Cite

show abstract

“…The estimated prevalence of schistosomiasis in African migrants, reported from a scarce European literature, ranged from 9–15% if based on use of microscopy [20,21] to 5.8–24.7% if based on ELISA serology [22,23]. Clearly, all data obtained from reference centers are to be taken with caution as they may not be representative of the general population.…”

Section: Introductionmentioning

confidence: 99%

Accuracy of parasitological and immunological tests for the screening of human schistosomiasis in immigrants and refugees from African countries: An approach with Latent Class Analysis

et al. 2017

View full text Add to dashboard Cite

BackgroundSchistosomiasis is a neglected infection affecting millions of people, mostly living in sub-Saharan Africa. Morbidity and mortality due to chronic infection are relevant, although schistosomiasis is often clinically silent. Different diagnostic tests have been implemented in order to improve screening and diagnosis, that traditionally rely on parasitological tests with low sensitivity. Aim of this study was to evaluate the accuracy of different tests for the screening of schistosomiasis in African migrants, in a non endemic setting.Methodology/Principal findingsA retrospective study was conducted on 373 patients screened at the Centre for Tropical Diseases (CTD) in Negrar, Verona, Italy. Biological samples were tested with: stool/urine microscopy, Circulating Cathodic Antigen (CCA) dipstick test, ELISA, Western blot, immune-chromatographic test (ICT). Test accuracy and predictive values of the immunological tests were assessed primarily on the basis of the results of microscopy (primary reference standard): ICT and WB resulted the test with highest sensitivity (94% and 92%, respectively), with a high NPV (98%). CCA showed the highest specificity (93%), but low sensitivity (48%). The analysis was conducted also using a composite reference standard, CRS (patients classified as infected in case of positive microscopy and/or at least 2 concordant positive immunological tests) and Latent Class Analysis (LCA). The latter two models demonstrated excellent agreement (Cohen’s kappa: 0.92) for the classification of the results. In fact, they both confirmed ICT as the test with the highest sensitivity (96%) and NPV (97%), moreover PPV was reasonably good (78% and 72% according to CRS and LCA, respectively). ELISA resulted the most specific immunological test (over 99%). The ICT appears to be a suitable screening test, even when used alone.ConclusionsThe rapid test ICT was the most sensitive test, with the potential of being used as a single screening test for African migrants.

show abstract

“…A high prevalence of schistosomiasis (9% to 60%) has been reported among adolescent migrants from sub-Saharan Africa re-settled in Germany, Switzerland, Spain, and Canada [53,95,97,98]. Schistosoma mansoni and S. haematobium are the two primary species of Schistomas causing intestinal and genitourinary disease, respectively.…”

Section: Intestinal and Tissue Parasitesmentioning

confidence: 99%

Children on the Move

Oberg¹

2020

View full text Add to dashboard Cite

Screening for infectious diseases among unaccompanied minor refugees in Berlin, 2014–2015

Cited by 51 publications

References 7 publications

‘I think we've had a health screen’: New offshore screening, new refugee health guidelines, new Syrian and Iraqi cohorts: Recommendations, reality, results and review

‘I think we've had a health screen’: New offshore screening, new refugee health guidelines, new Syrian and Iraqi cohorts: Recommendations, reality, results and review

Accuracy of parasitological and immunological tests for the screening of human schistosomiasis in immigrants and refugees from African countries: An approach with Latent Class Analysis

Children on the Move

Contact Info

Product

Resources

About