Screening for Language Disorders in Stroke: German Validation of the Language Screening Test (LAST)

Koenig-Bruhin, Monica; Vanbellingen, Tim; Schumacher, Rahel; Pflugshaupt, Tobias; Annoni, Jean Marie; Müri, René M.; Bohlhalter, Stephan; Nyffeler, Thomas

doi:10.1159/000445778

Cited by 13 publications

(12 citation statements)

References 12 publications

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“…The Language Screening Test (LAST) in French generated by Constance Flamand-Roze, which was designed for aphasia screening in emergency setting, avoids the aforementioned shortcomings and has been proved to be suitable for routine bedside evaluation of patients with acute stroke in clinical practice[ 9 ]. The released German version of the LAST has also been proved to be reliable and valid[ 21 ]. Therefore, LAST may has good language flexibility or compatibility and can be easily tailored into a different language version by making some slight modifications according to a certain linguistic and cultural context.…”

Section: Introductionmentioning

confidence: 99%

A Chinese version of the Language Screening Test (CLAST) for early-stage stroke patients

et al. 2018

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There is a severe lack of aphasia screening tools for bedside use in Chinese. A number of aphasia assessment tools have recently been developed abroad, but some of these scales were not suitable for patients with acute stroke. The Language Screening Test (which includes two parallel versions [a/b]) in French has been proven to be an effective and time-saving aphasia screening scale for early-stage stroke patients. Therefore, we worked out a Chinese version of the LAST taking into consideration Chinese language and culture. Two preliminary parallel versions (a/b) were tested on 154 patients with stroke at acute phase and 107 patients with stroke at non-acute phase, with the Western Aphasia Battery serving as a gold standard. The equivalence between the two parallel versions and the reliability/validity of each version were assessed. The median time to complete one preliminary Chinese version (each had some item redundancy) was 98 seconds. Two final parallel versions were established after adjustment/elimination of the redundant items and were found to be equivalent (intra-class correlation coefficient: 0.991). Internal consistency is(Cronbach α for each version [a/b] was 0.956 and 0.965, respectively) good. Internal validity was fine: (a) no floor or ceiling effect/item redundancy; (b) construct validity revealed a 1-dimension structure, just like the French version. The higher educated subjects scored higher than their lower educated counterparts (p<0.01). The external validity: at the optimum cut-off point where the score of version a/b <14 in higher educated group(<13 in lower): the specificity of each version was 0.878/0.902(1/1 in lower) and sensitivity was 0.972/0.944(0.944/0.944 in lower). Inter-rater equivalence (intra-class correlation coefficient) was 1. The Chinese version of the Language Screening Test was proved to be an efficient and time-saving bedside aphasia screening tool for stroke patients at acute phase and can be used by an average medical physician.

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Section: Introductionmentioning

confidence: 99%

A Chinese version of the Language Screening Test (CLAST) for early-stage stroke patients

et al. 2018

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“…Patients were selected according to the following criteria: inclusion criteria were: (1) written informed consent, (2) aged above 18 years, (3) a first-ever stroke in the past 24 h until 3 months, reflecting the early rehabilitation phase ( 5 ) (4) experience upper limb impairments due to stroke (Nine Hole Peg Test > 19 s with at least one side) ( 28 ), (5) at least able to perform ante-flexion with their upper arm and extent one or more fingers against gravity (3 ≤ Medical Research Council scale < 5) ( 29 ), and (6) the participants had to be able to understand the instructions and assessments in German. Exclusion criteria were: (1) severe cognitive impairments (Montreal Cognitive assessment: MoCa < 14) ( 30 ), (2) severe apraxia (Apraxia Screen of TULIA < 9) ( 31 ), (3) aphasia (Language screening test < 15) ( 32 ), (4) severe self-reported pain, or (5) other severe orthopedic problems of the upper limb impairing participation.…”

Section: Methodsmentioning

confidence: 99%

Usability of Videogame-Based Dexterity Training in the Early Rehabilitation Phase of Stroke Patients: A Pilot Study

et al. 2017

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BackgroundApproximately 70–80% of stroke survivors have limited activities of daily living, mainly due to dexterous problems. Videogame-based training (VBT) along with virtual reality seems to be beneficial to train upper limb function.ObjectiveTo evaluate the usability of VBT using the Leap Motion Controller (LMC) to train fine manual dexterity in the early rehabilitation phase of stroke patients as an add-on to conventional therapy. Additionally, this study aimed to estimate the feasibility and potential efficacy of the VBT.MethodsDuring 3 months, 64 stroke patients were screened for eligibility, 13 stroke patients were included (4 women and 9 men; age range: 24–91 years; mean time post stroke: 28.2 days).InterventionNine sessions of 30 min VBT, three times per week as an add-on to conventional therapy with stroke inpatients.Outcome measuresPrimary outcome was the usability of the system measured with the System Usability Scale. Secondary outcomes concerning feasibility were the compliance rate calculated from the total time spent on the intervention (TT) compared to planned time, the opinion of participants via open-end questions, and the level of active participation measured with the Pittsburgh Rehabilitation Participation Scale. Regarding the potential efficacy secondary outcomes were: functional dexterity measured with the Nine Hole Peg Test (NHPT), subjective dexterity measured with the Dexterity Questionnaire 24, grip strength measured with the Jamar dynamometer, and motor impairment of the upper limb measured with the Fugl-Meyer Upper Extremity (FM-UE) scale.ResultsPrimarily, the usability of the system was good to excellent. The patient’s perception of usability remained stable over a mean period of 3 weeks of VBT. Secondly, the compliance rate was good, and the level of active participation varied between good and very good. The opinion of the participants revealed that despite individual differences, the overall impression of the therapy and device was good. Patients showed significant improvements in hand dexterity. No changes were found in motor impairment of the upper limb (FM-UE) during intervention.ConclusionVBT using LMC is a usable rehabilitation tool to train dexterity in the early rehabilitation phase of stroke inpatients.

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“…Screening for aphasia will be performed using the Language Screening Test (LAST) (25,26). The LAST is a simple, quick, validated screening instrument focusing on speech comprehension, word repetition, and naming.…”

Section: Interventional Methodsmentioning

confidence: 99%

“…A total score of 15 can be achieved, meaning one point per item. The minimum number of points that can be attained is 0 (25,26). In clinical trials, there is no validation of severity of aphasia using the LAST; however, based on clinical experience and consensus, the severity of aphasia is as follows: 0-5 severe, 6-10 moderate, and 11-14 minimal.…”

Section: Interventional Methodsmentioning

confidence: 99%

Follow-Up in Aphasia Caused by Acute Stroke in a Prospective, Randomized, Clinical, and Experimental Controlled Noninvasive Study With an iPad-Based App (Neolexon®): Study Protocol of the Lexi Study

Thunstedt

Young²,

Küpper

et al. 2020

Front. Neurol.

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Rationale: Treatment of aphasia is still challenging for clinicians and patients. So far, there is proven evidence for "face-to-face" speech therapy. However, the digital age potentially offers new and complementary strategies that may add to treatment outcome in a cost-effective way. Neolexon ® is a commercial tablet-based software for treatment of aphasia, which can be applied with the help of a therapist or as self-training by the patient. Aims and hypothesis: In the Lexi study, we aim to determine whether treatment with Neolexon ® is superior to standard therapy in acute post-stroke aphasia. Sample size estimates: A sample size of 180 patients, 90 for each group, will be included with an assumed dropout rate of ∼20%. Methods and design: Prospective, randomized, parallel group, open-label, blinded-endpoint clinical, and experimental controlled non-invasive trial (PROBE). Adult German native speakers with acute aphasia after stroke are included. Computer-generated, blocked, and stratified randomization by aphasia severity will assign patients to one of two groups: 4 weeks of either standard logopedic speech therapy or logopedic speech therapy with the app version of Neolexon ®. Both groups will be instructed in self-training: the frequency and duration of self-training will be documented. Screening for aphasia will be performed using the Language Screening Test (LAST). The severity of aphasia in general and in subitems will be assessed using the Bielefelder Aphasie Screening (BIAS) and the Aphasia Check List (ACL). Follow-up will be assessed after 3 months. Study outcomes: Based on the consensus in our study team, we considered a 10% mean difference in the change of percentile rank (PR) of BIAS to be a minimal and clinically Thunstedt et al. The Tablet-Based Lexi Study important difference. The primary endpoint is defined as a significant difference in BIAS comparing the two groups. Differences in quality of life, Beck Depression Inventory (BDI), and modified Ranking Scale (mRS) will be evaluated as secondary outcome parameters. Discussion: This trial will determine whether speech therapy with the use of Neolexon ® is superior to standard logopedic therapy. Subgroups with the greatest response to Neolexon ® will be described. The trial was prospectively registered on the "EU Clinical Trials Register" (NCT04080817) 1 .

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Screening for Language Disorders in Stroke: German Validation of the Language Screening Test (LAST)

Cited by 13 publications

References 12 publications

A Chinese version of the Language Screening Test (CLAST) for early-stage stroke patients

A Chinese version of the Language Screening Test (CLAST) for early-stage stroke patients

Usability of Videogame-Based Dexterity Training in the Early Rehabilitation Phase of Stroke Patients: A Pilot Study

Follow-Up in Aphasia Caused by Acute Stroke in a Prospective, Randomized, Clinical, and Experimental Controlled Noninvasive Study With an iPad-Based App (Neolexon®): Study Protocol of the Lexi Study

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