Screening for local and regional cancer recurrence in patients curatively treated for laryngeal cancer: Definition of a high‐risk group and estimation of the lead time

Abstract

Risk profiles for locoregional relapse were defined. Intensifying the follow-up schedule is not advisable because the lead time is very short. An excessively high number of routine visits would have to be performed to increase the detection rate for asymptomatic recurrences.

Patient and tumor factors at diagnosis in a multi‐ethnic primary head and neck squamous cell carcinoma cohort

“…These findings are consistent with previous studies demonstrating histologic tumor grade as a powerful predictor of distant metastasis, adding important information to clinical and pathologic neck staging, including consideration for systemic treatment [16]. Histologic grade also emerged as a significant risk factor of local or regional laryngeal cancer recurrence [17]. The 1998 National Cancer Data Base (NCDB) Report on Cancer of the Head and Neck [9] reported that poorly differentiated head and neck cancers were most notably associated with advanced stage.…”

Impact of surveillance on survival after laryngeal cancer in the medicare population

“…This study challenges the belief that routine surveillance improves survival after laryngeal cancer recurrence. Consistent with previous reports,11, 12, 25 there was no difference in overall postrecurrence laryngeal cancer survival based on surveillance intensity. However, in subsite analysis, a survival advantage was apparent for patients with recurrent glottic cancer.…”

Prognostic value of continued smoking on survival and recurrence rates in patients with head and neck cancer: A systematic review

“…Cross‐reference checking revealed no additional relevant articles. A total of 12 articles were selected for study assessment …”

“…Twelve articles were assessed for their relevance and risk of bias . Nine articles were characterized by a high relevance and the other 3 studies by a moderate relevance. The follow‐up duration or time interval in determining recurrence was unknown in 2 studies .…”