Abstract:Contact investigation is a key component of tuberculosis (TB) control in developed, but not developing, countries. We aimed to measure the prevalence of TB among household contacts of sputum-smear-positive TB cases in The Gambia and to assess the sensitivity of an enzyme-linked immunospot (ELISPOT) assay in this regard. Household contacts of adult smear-positive TB patients were assessed by questionnaire, purified protein derivative (PPD) skin test, ELISPOT assay, physical examination, chest X-ray and sputum/g… Show more
“…21 In settings using passive case detection, more TB cases are male than female; the male to female ratio is more evenly balanced when active case detection is used. 22 It should be noted that around 60% of study samples from Tongatapu were from males, whereas just over 50% of sputum samples were from males in the outer islands. This may be a chance finding, but requires further …”
“…21 In settings using passive case detection, more TB cases are male than female; the male to female ratio is more evenly balanced when active case detection is used. 22 It should be noted that around 60% of study samples from Tongatapu were from males, whereas just over 50% of sputum samples were from males in the outer islands. This may be a chance finding, but requires further …”
“…They found that the patients were less advanced than those found through passive case detection. [15] In Hong Kong, China, the household contact survey was also followed-up and considered to be a useful method in the detection of TB patients. [16] In our study, the index patients were not divided into MB and PB for analysis because the MB patients accounted for 87.9% of all newly detected patients in China.…”
The authors conclude that at the time of a low leprosy endemic situation, the household contact survey is still a useful method for case detection in China.
“…Studies done in child contacts in African communities have shown that one-third to two-thirds of child household contacts of TB cases have evidence of TB infection (ie, TST-positive) [12,13]. Of children with TB, 70% to 80% have the disease in their lungs (pulmonary TB, PTB).…”
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