2006
DOI: 10.1016/j.phymed.2005.03.009
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Screening of antiradical and antioxidant activity of monodesmosides and crude extract from Leontice smirnowii tuber

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Cited by 141 publications
(54 citation statements)
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“…Subsequently, evaluation of all isolated compounds will be needed to confirm the active component. Many studies have shown that antioxidant properties, especially radical scavenging activities, are very important due to the deleterious role of free radicals in foods and in biological systems (Gülçin et al, 2006) and antioxidant capacity is widely used as a parameter to characterize food or medicinal plants and their bioactive components . The hydroxyl radical which is a very reactive species that is formed in biological systems has been implicated as a highly damaging species in free radical pathology, capable of damaging almost every molecule found in living cells.…”
Section: Resultsmentioning
confidence: 99%
See 1 more Smart Citation
“…Subsequently, evaluation of all isolated compounds will be needed to confirm the active component. Many studies have shown that antioxidant properties, especially radical scavenging activities, are very important due to the deleterious role of free radicals in foods and in biological systems (Gülçin et al, 2006) and antioxidant capacity is widely used as a parameter to characterize food or medicinal plants and their bioactive components . The hydroxyl radical which is a very reactive species that is formed in biological systems has been implicated as a highly damaging species in free radical pathology, capable of damaging almost every molecule found in living cells.…”
Section: Resultsmentioning
confidence: 99%
“…Several of these substances may interfere with the oxidation process by reacting with free radicals . When these species had an excessive formation induces oxidative damage to biomolecules, which eventually causes numerous diseases (Gülçin et al, 2006;Edewor-Kuponiyi, 2013). .…”
Section: Introductionmentioning
confidence: 99%
“…Superoxide has also been observed to directly initiate lipid peroxidation [67]. It has also been reported that the antioxidant properties of some flavonoids are effective mainly via scavenging of superoxide anion radical [68,69]. Superoxide anion plays an important role in the formation of other ROS such as hydrogen peroxide, hydroxyl radical, and singlet oxygen, which induce oxidative damage in lipids, proteins, and DNA [70].…”
Section: Radical Scavenging Activitymentioning
confidence: 99%
“…Reactive oxygen species (ROS) damage living cells causing lipid, protein, and DNA oxidation (Shukla et al, 2010). They are involved in the development of various diseases such as diabetes, rheumatic disorders (Luximon-Ramma et al, 2002), aging, cancer, cardiovascular or neurodegenerative disorders (Ju et al, 2004;Tarnawski et al, 2005), malaria and gastric ulcer (Gülçin et al, 2006).…”
Section: Introductionmentioning
confidence: 99%
“…These natural products could be used in food or in medicinal materials to replace synthetic antioxidants which are about to be restricted owing to their side effects such as carcinogenesis (Gülçin et al, 2006). Many medicinal plants contain large amounts of antioxidants, such as polyphenols, which can play an important role in adsorbing and neutralizing free radicals, in quenching singlet and triplet oxygen, or in decomposing peroxides.…”
Section: Introductionmentioning
confidence: 99%